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The official blog of Cell Signaling Technology, where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Pancreatic Cancer: Targeting Novel Drivers in the Tumor Microenvironment

Pancreatic cancer is devastating and difficult to diagnose early. The organ is located deep inside t...
Andrea Tu, PhD Apr 27, 2022

Melanoma: Aberrant Signaling Pathways and Therapeutic Approaches

There are three major types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melan...
Andrea Tu, PhD Mar 30, 2022

Emerging Therapeutic Approaches for Prostate Cancer

Approximately one in eight men will be diagnosed with prostate cancer during their lifetime, making ...
Andrea Tu, PhD Feb 23, 2022

Cancer Biomarker Antibody Selection for IHC

What are cancer biomarkers? Biomarkers are naturally occurring molecules that can be used as indicat...

The Role of Metabolism in Cancer

Alterations in the cellular metabolism of malignant cells have long been a central focus of cancer r...
Chris Sumner Mar 24, 2021

Targeting TIGIT for Cancer Immunotherapy & T Cell Exhaustion

The evolution of solid tumor cancer treatment has historically centered on a tripartite approach tha...
Tamar Aprahamian, PhD Feb 17, 2021

T Cell Basics: What a Disease Researcher Needs to Know

T cells are highly specialized lymphocytes that play a critical role in the cell-mediated arm of the...
Tamar Aprahamian, PhD Nov 11, 2020

10 Must-Have Markers for Senescence Research

Understanding when and why cell cycle arrest occurs is critical to many fields of research, includin...
Tamar Aprahamian, PhD May 13, 2020

Fibrosis: When Wound Healing Turns to Disease

Fibrosis is a disease that is characterized by scarring and hardening of tissues and organs. Fibrosi...
Susan Keezer, PhD Mar 25, 2020

IMC: Endless Possibilities to Understand the Microenvironment of Disease

Understanding the microenvironment of disease is critical. Targeted cancer therapies may not be effe...

The Researcher's Guide to the Hallmarks of Cancer Research Targets

If you haven’t heard already, it’s CST’s 20th anniversary. Woohoo! You could say this year is kind o...
Chris Sumner Oct 9, 2019

Hallmarks of Cancer: Tumor-Promoting Inflammation

Cancer cells hijack inflammatory mechanisms to promote their own growth and survival. During a norma...
Chris Sumner Aug 21, 2019

The BAFfling Complexity of the BAF Complex in Cancer

How do cells dynamically regulate access to their tightly packed DNA to control gene expression and ...
Curtis Desilets Jul 24, 2019

Hallmarks of Cancer: Activating Invasion and Metastasis

Cancer cells invade local tissue and spread to distant sites via two distinct, but similar processes...
Chris Sumner Jul 17, 2019

Pathways to Cancer: Epithelial-Mesenchymal Transition

The process of epithelial-mesenchymal transition (EMT), whereby differentiated epithelial cells tran...
Antony Wood, PhD May 29, 2019

Hallmarks of Cancer: Evading Growth Suppressors

Cancer cells resist inhibitory signals that might otherwise stop their growth. The major pathways in...
Chris Sumner May 1, 2019

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