CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Lab Expectations listing page

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Autophagy: It’s a Cell-Eat-Self World

If the thought of self-cannibalization is not appealing to you, you may not want to read the next se...
Alexandra Foley May 22, 2024

IHC-Validated p16 INK4A Antibody: Jump-Start Your Senescence Research

Cell cycle regulation is vital to maintain tissue homeostasis and to prevent sustained proliferative...
Andrea Tu, PhD Apr 19, 2023

Emerging Discoveries in ER-Phagy

Autophagy is a catabolic process for the disposal of cytoplasmic contents that are captured by doubl...
Gary Kasof, PhD Nov 3, 2021

Assay Kits and Tools for Monitoring Cell State

Have you been wondering how to monitor a cell state or cellular response? From a basic research stan...
Andrea Tu, PhD Oct 6, 2021

Xenophagy: What You Eat Can’t Hurt You

Xenophagy provides an important defense against foreign pathogens such as bacteria and viruses by ta...
Gary Kasof, PhD Sep 15, 2021

Understanding Mitophagy

Mitochondrial health is a complex, carefully regulated process involving pathways that determine mit...
Gary Kasof, PhD Aug 11, 2021

Mechanisms of Cell Death: Ferroptosis

What is ferroptosis? Ferroptosis is an iron-dependent form of programmed cell death with distinct mo...
Gary Kasof, PhD Jun 2, 2021

Mechanisms of Cell Death: Necrosis & Necroptosis

The thought of necrotic cell death might bring to mind images from an old horror movie, but as with ...
April Lowell, PhD Apr 28, 2021

Mechanisms of Cell Death: Pyroptosis

Under the category of necrotic cell death, there are many well-characterized, as well as some newly ...
April Lowell, PhD Apr 7, 2021

Mechanisms of Cell Death: Apoptosis

The death of a cell may be a more complex process than one might initially imagine. Cells expire in ...
April Lowell, PhD Mar 10, 2021

The Role of Autophagy and ER Stress in Viral Infection

The regulation of ER stress and autophagy during viral infection is an important factor in the balan...
Gary Kasof, PhD Oct 28, 2020

The Role of Cell Death in Viral Infection

The regulation of cell death during viral infection is an important factor in the balance of virus a...
Gary Kasof, PhD Oct 21, 2020

Cell Process: Which markers can be used to identify cellular senescence?

In response to a variety of environmental factors—like ionizing radiation, exposure to chemotherapeu...
Tamar Aprahamian, PhD Oct 14, 2020

Cell Process: What role does senescence play in disease?

Cellular senescence occurs when cells cease proliferation and irreversibly exit the cell cycle. Whil...
Tamar Aprahamian, PhD Oct 7, 2020

Cell Process: What role do the telomeres play in senescence?

Senescence is a cellular state during which cells remain metabolically active, but irreversibly with...
Tamar Aprahamian, PhD Sep 16, 2020

Cell Process: How is cellular senescence related to aging?

Senescence, the cessation of cell division and permanent withdrawal from the cell cycle, is a proces...
Tamar Aprahamian, PhD Sep 9, 2020

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