CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Validating a Monoclonal Antibody for the ADP-Ribosylation PTM

Protein adenosine diphosphate, or ADP-ribosylation, is a fascinating post-translational modification...

How to Detect Protein Methylation Using Proteomics

Protein methylation is a ubiquitous and critical post-translational modification (PTM) in eukaryotes...

Got the 'NOS'? Fueling Research with New Nitro-Tyrosine Antibody Tools

Since 2000, Cell Signaling Technology (CST) has offered a rigorously tested and well-cited polyclona...

Reproducibility in Proteomics Experiments: Using Control Peptides with PTMScan

Proteomics, the large-scale analysis of proteins, has become an increasingly important tool for iden...

The Kinase Library: How Big Data Can Help Identify Novel Kinase Drug Targets

Protein kinases play a vital role in the regulation of nearly all cellular activities. Through phosp...
Alexandra Foley May 3, 2023

A Revolution in Proteomics Analysis: PTMScan 20 Years Later

Twenty years ago, when considering the tools needed for more robust proteomics research to probe cel...

The Biopharma Trends to Watch in 2023, According to CST Scientists

Technological innovation leads to a deeper understanding of the natural world and the underlying cau...
Alexandra Foley Jan 18, 2023

Trim-Away: Rapid, Easy, and Specific Protein Degradation

Foundational approaches for studying protein function in living models—gene editing and RNA interfer...

It's All about the Affinity

In 2012 Roux et al. published in the Journal of Cell Biology a pioneering approach to identify the i...

Antibodies for Identifying the Protein Modification O-GlcNAc

Rajan Burt, Samuel Myers, and colleagues from the La Jolla Institute for Immunology, Broad Institute...

Using SignalScan to Investigate Infection and Immune Response

The highly contagious severe acute respiratory syndrome coronavirus-2 or SARS-CoV-2 is the cause of ...

Case Study: Acetylated Lysine and Its Impact on Crohn’s Disease

Nature Communications recently published a novel study from the laboratory of Daniel Figeys at the U...

Taking Out the Mitochondria in Parkinson’s Disease

We’re proud to partner with The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to move Pa...
Richard Cho, PhD Jul 31, 2019

Webinar | Proteomics profiling of post-translational modifications in early drug discovery

Advances in mass spectrometry instrumentation and sample handling methods have propelled proteomics ...
Chris Sumner Mar 28, 2018

Webinar | Post-translational Modification: Antibody Enrichment for Mass Spectrometry-based Proteomics

PTMScan Proteomics: Identification and Quantification of Post-Translationally Modified Peptides Prot...
Chris Sumner Nov 15, 2017

The Potential of Proteomics: A Clear Path to Discovery | Part II

See a real life example of how PTMScan technology can facilitate translational discovery. In this sh...
Carolyn P Feb 22, 2017

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