CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST) where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Stress Granules: What are they and what role do they play in neurodegenerative diseases?

Stress granules (SGs) are an important cellular defense mechanism against stress. Their formation is...
Jordan Hoffman May 24, 2023

SfN 2022: Ups and Downs in Neurodegenerative Research—New Tools, Models, and Technologies

In November, nearly 25,000 neuroscientists from all over the world gathered once again for the Socie...
Richard Cho, PhD Jan 6, 2023

Multiplexing the Brain: A Galaxy of Possibilities

The average human brain contains over 100 billion cells, which is nearly the same number as there ar...
Richard Cho, PhD Dec 15, 2021

Tools for Monitoring Cell State

Have you been wondering how to monitor a cell state or cellular response? From a basic research stan...
Andrea T Oct 6, 2021

Neuroinflammation in Neurodegenerative Diseases

Neuroinflammation is the activation of an immune response in the central nervous system (CNS; brain ...
Chris Sumner Jun 23, 2021

Autophagy: Taking Out the Cellular Trash Has Widespread Therapeutic Implications

The term “autophagy” introduced by the biochemist Christian de Duve in 1963 is derived from the Gree...
Gary Kasof, PhD Jun 16, 2021

Neurotransmitters, Receptors, and Transporters

What is neurotransmission? Neurons are central nervous system (CNS) cells that receive and transmit ...
Chris Sumner May 19, 2021

The Role of Neural and Glial Cell Markers

The central nervous system (CNS) is composed of highly specialized cells, each playing a key role in...
Chris Sumner Apr 14, 2021

Which Antibody-Based Techniques Can Be Used to Study Neurodegenerative Diseases?

In order to derive the most information from samples related to neurodegenerative disease, it is imp...
Chris Sumner Mar 17, 2021

Neurodegeneration: Tau Protein and Neurofibrillary Tangles

Tau is a microtubule-associated protein expressed predominantly in the parts of the brain that funct...
Chris Sumner Feb 10, 2021

What Is Neurodegenerative Disease?

Neurodegeneration is marked by the progressive loss of neuronal function and structure leading to co...
Chris Sumner Jan 20, 2021

Chasing Tau-biomarkers for Alzheimer’s Disease [Part 2]

This is Part 2 of a two-part blog series on Alzheimer's Disease. Read Part 1 here.   What plasma bio...
Antonio V and Lei L Jan 13, 2021

Chasing Tau-biomarkers for Alzheimer’s Disease [Part 1]

Dementia is an inevitable burden for many, prevailing under a broad umbrella not only in neurologica...
Antonio V and Lei L Dec 2, 2020

Tissue Clearing from a Microscope Enthusiast’s Perspective

Biological imaging data has massive potential in terms of complexity of experiment and richness of d...
Ginny Bain, PhD Oct 30, 2019

Taking Out the Mitochondria in Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative disease marked by loss of dopaminergic neurons in th...
Richard C and Yiying Z Jul 31, 2019

If I Could Only See What’s Going on Inside Your Brain...

For generations of neuroscientists, using immunohistochemistry to study the brain in its anatomical ...
Richard Cho, PhD Jun 5, 2019

ApoE4 and the Insulin Receptor — It's a Trap!

You might be surprised to learn that diabetes, a metabolic disease, may be linked to the neurodegene...
Richard Cho, PhD Aug 1, 2018

Still in the Dark: AMD Patients Wait for Answers

In Mr. D’s sophomore English class, almost no subject was taboo or off limits. Even with our class p...
Chris Sumner Apr 11, 2018

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