CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology® (CST) where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Multiplexing the Brain: A Galaxy of Possibilities

The average human brain contains over 100 billion cells, which is nearly the same number as there ar...
Richard C Dec 15, 2021

Tools for Monitoring Cell State

Have you been wondering how to monitor a cell state or cellular response? From a basic research stan...
Andrea T Oct 6, 2021

Neuroinflammation in Neurodegenerative Diseases

Neuroinflammation is the activation of an immune response in the central nervous system (CNS; brain ...
Chris S Jun 23, 2021

Autophagy: Taking Out the Cellular Trash Has Widespread Therapeutic Implications

The term “autophagy” introduced by the biochemist Christian de Duve in 1963 is derived from the Gree...
Gary K Jun 16, 2021

Neurotransmitters, Receptors, and Transporters

What is neurotransmission? Neurons are central nervous system (CNS) cells that receive and transmit ...
Chris S May 19, 2021

The Role of Neural and Glial Cell Markers

The central nervous system (CNS) is composed of highly specialized cells, each playing a key role in...
Chris S Apr 14, 2021

Which Antibody-Based Techniques Can Be Used to Study Neurodegenerative Diseases?

In order to derive the most information from samples related to neurodegenerative disease, it is imp...
Chris S Mar 17, 2021

Neurodegeneration: Tau Protein and Neurofibrillary Tangles

Tau is a microtubule-associated protein expressed predominantly in the parts of the brain that funct...
Chris S Feb 10, 2021

What Is Neurodegenerative Disease?

Neurodegeneration is marked by the progressive loss of neuronal function and structure leading to co...
Chris S Jan 20, 2021

Chasing Tau-biomarkers for Alzheimer’s Disease [Part 2]

This is Part 2 of a two-part blog series on Alzheimer's Disease. Read Part 1 here.   What plasma bio...
Antonio V and Lei L Jan 13, 2021

Chasing Tau-biomarkers for Alzheimer’s Disease [Part 1]

Dementia is an inevitable burden for many, prevailing under a broad umbrella not only in neurologica...
Antonio V and Lei L Dec 2, 2020

Tissue Clearing from a Microscope Enthusiast’s Perspective

Biological imaging data has massive potential in terms of complexity of experiment and richness of d...
Ginny B Oct 30, 2019

Taking Out the Mitochondria in Parkinson’s Disease

Parkinson’s disease (PD) is a neurodegenerative disease marked by loss of dopaminergic neurons in th...
Richard C and Yiying Z Jul 31, 2019

If I could only see what’s going on inside your brain...

For generations of neuroscientists, using immunohistochemistry to study the brain in its anatomical ...
Richard C Jun 5, 2019

ApoE4 and the Insulin Receptor — It's a Trap!

You might be surprised to learn that diabetes, a metabolic disease, may be linked to the neurodegene...
Richard C Aug 1, 2018

Still in the Dark: AMD Patients Wait for Answers

In Mr. D’s sophomore English class, almost no subject was taboo or off limits. Even with our class p...
Chris S Apr 11, 2018

SfN 2017 Recap: Lonely Neuron No More

In Nov 2017, over 30,000 neuroscientists gathered in Washington D.C. to talk all things brain at the...
Richard C Dec 13, 2017

Journal Club: TREM2 Opens a Rabbit Hole of Questions for Alzheimer’s Researchers

It's almost time for the 2017 Society for Neuroscience meeting. To get your neurons excited for the ...
Richard C Nov 8, 2017

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