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Immunology: What are myeloid cells and how are they identified?

During hematopoiesis, myeloid cells develop from a common myeloid progenitor (CMP) found in the bone...
Rob MacDonald, PhDMay 22, 2025

Immunology: What are lymphoid cells and how are they identified?

In humans, hematopoietic stem cells (HSCs) continuously replenish all types of blood cells via a ser...
Amrik Singh, PhDMay 21, 2025

Do mRNA and protein levels correlate? Not necessarily.

To what extent does mRNA dictate cellular protein levels? It depends. For decades, scientists have u...
Tyler LevyApr 23, 2025

The Importance of the ISG15 Protein in COVID-19 Research

Historically, the ISG15 protein hasn’t been thoroughly investigated by researchers. We know it can f...

Xenophagy: What You Eat Can’t Hurt You

Xenophagy provides an important defense against foreign pathogens such as bacteria and viruses by ta...
Gary Kasof, PhDSep 15, 2021

Immunology: Immunophenotyping Using Flow Cytometry or IHC

In the field of immunology and immuno-oncology, immunophenotyping is a technique that uses antibodie...
Chris SumnerJun 30, 2021

Neuroinflammation in Neurodegenerative Diseases

Neuroinflammation is the activation of an immune response in the central nervous system (CNS; brain ...
Chris SumnerJun 23, 2021

Mechanisms of Cell Death: Pyroptosis

Pyroptosis is a form of regulated necrotic cell death that ties the danger-sensing capabilities of t...
Gary Kasof, PhDApr 7, 2021

Case Study: Acetylated Lysine and Its Impact on Crohn’s Disease

Nature Communications recently published a novel study from the laboratory of Daniel Figeys at the U...

B Cell Basics: Markers, Signaling Pathways & Immune Outcomes

Changes in the activation of intracellular signaling networks downstream of B-cell receptors (BCR) l...
Tamar Aprahamian, PhDNov 18, 2020

T Cell Basics: What a Disease Researcher Needs to Know

T cells are highly specialized lymphocytes that play a critical role in the cell-mediated arm of the...
Tamar Aprahamian, PhDNov 11, 2020

COVID-19 and Fibrosis: Long-term Damage Beyond Acute Respiratory Symptoms

At the time of writing, the SARS-CoV-2 virus, responsible for COVID-19, has infected more than 28 mi...
Antony Wood, PhDNov 4, 2020

The Role of Autophagy and ER Stress in Viral Infection

The regulation of ER stress and autophagy during viral infection is an important factor in the balan...
Gary Kasof, PhDOct 28, 2020

The Role of Cell Death in Viral Infection

The regulation of cell death during viral infection is an important factor in the balance of virus a...
Gary Kasof, PhDOct 21, 2020

How can recombinant proteins help researchers study SARS-CoV-2?

Although coronaviruses have long circulated throughout human populations, the study of these viruses...

Immunology: How does the adaptive immune system work?

Have you ever wondered how people are able to develop immunity to specific diseases? This important ...
April Lowell, PhDJul 29, 2020

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