CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Mechanisms of Cell Death: Apoptosis

What is apoptosis? Apoptosis is a form of programmed cell death (PCD) characterized by cell shrinkag...
Gary Kasof, PhD Jun 18, 2025

Mapping RNA-Protein Interactions with RBP-eCLIP: Powering Discovery in RNA Biology

Guest author Dr Vince Harjono is an Application Scientist Manager at Eclipsebio. CST and Eclipsebio ...

M6A: A Cell’s Hidden Signal of Gene Regulation Through RNA

Guest author Gina Lee, PhD, is an Assistant Professor of Microbiology and Molecular Genetics at the ...
Gina Lee, PhD Sep 28, 2022

Hypoxia and Its Role in Metabolism

Hypoxia—the deficiency of oxygen in the cellular environment—causes cellular stress and alters norma...
Chris Sumner Jun 8, 2022

Tools for Classifying Cells and Identifying Protein Localization

When do I want to classify cells? Why do I care where a protein localizes? These are actually two di...
Andrea Tu, PhD Jan 26, 2022

Emerging Discoveries in ER-Phagy

Autophagy is a catabolic process for the disposal of cytoplasmic contents that are captured by doubl...
Gary Kasof, PhD Nov 3, 2021

The Role of Metabolism in Disease

Metabolism plays a central role in many diseases including diabetes, cardiovascular disease, obesity...
Chris Sumner Oct 27, 2021

Tools for Modulating Cells

Cell behavior is a tightly regulated, finely tuned process where various different signals work toge...
Andrea Tu, PhD Oct 13, 2021

Assay Kits and Tools for Monitoring Cell State

Have you been wondering how to monitor a cell state or cellular response? From a basic research stan...
Andrea Tu, PhD Oct 6, 2021

Xenophagy: What You Eat Can’t Hurt You

Xenophagy provides an important defense against foreign pathogens such as bacteria and viruses by ta...
Gary Kasof, PhD Sep 15, 2021

Understanding Mitophagy: Pathways, Disease Links, and Tools for Detection

Mitochondrial health is a complex, carefully regulated process involving pathways that determine mit...
Gary Kasof, PhD Aug 11, 2021

Autophagy: Taking Out the Cellular Trash Has Widespread Therapeutic Implications

The term “autophagy” introduced by the biochemist Christian de Duve in 1963 is derived from the Gree...
Gary Kasof, PhD Jun 16, 2021

Mechanisms of Cell Death: Ferroptosis

What is ferroptosis? Ferroptosis is an iron-dependent form of programmed cell death with distinct mo...
Gary Kasof, PhD Jun 2, 2021

What is glycolysis and what is its role in metabolism?

Glycolysis and oxidative respiration are the two major metabolic pathways cells employ in order to c...
Chris Sumner May 26, 2021

Unraveling the Role of G3BPs in the Regulation of Cellular Energetics

In an article published by Prentzell et al in Cell, scientists used around 30 different CST antibodi...

Mechanisms of Cell Death: Necrosis & Necroptosis

The thought of necrotic cell death might bring to mind images from an old horror movie, but as with ...
April Lowell, PhD Apr 28, 2021

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