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Mechanisms of Cell Death: Ferroptosis

What is ferroptosis? Ferroptosis is an iron-dependent form of programmed cell death with distinct mo...
Gary Kasof, PhD Jul 9, 2025

Mechanisms of Cell Death: Apoptosis

What is apoptosis? Apoptosis is a form of programmed cell death (PCD) characterized by cell shrinkag...
Gary Kasof, PhD Jun 18, 2025

Mapping RNA-Protein Interactions with RBP-eCLIP: Powering Discovery in RNA Biology

Guest author Dr Vince Harjono is an Application Scientist Manager at Eclipsebio. CST and Eclipsebio ...

Key Epithelial-Mesenchymal Transition (EMT) Markers in Cancer

EMT, or epithelial-mesenchymal transition, is a biological process in which epithelial cells gain th...
Susan Keezer, PhD Jun 4, 2025

Targeting the Tumor Microenvironment: Key Markers of the Extracellular Matrix (ECM)

In recent years, cancer researchers have started paying closer attention to the extracellular matrix...
Susan Keezer, PhD May 28, 2025

Immunology: What are myeloid cells and how are they identified?

During hematopoiesis, myeloid cells develop from a common myeloid progenitor (CMP) found in the bone...
Rob MacDonald, PhD May 22, 2025

Immunology: What are lymphoid cells and how are they identified?

In humans, hematopoietic stem cells (HSCs) continuously replenish all types of blood cells via a ser...
Amrik Singh, PhD May 21, 2025

Do mRNA and protein levels correlate? Not necessarily.

To what extent does mRNA dictate cellular protein levels? It depends. For decades, scientists have u...
Tyler Levy Apr 23, 2025

Why is combining single cell RNA and intracellular signaling data difficult?

What if you could measure RNA, determine cell type, and detect intracellular signaling, all in a sin...
Alexandra Foley Feb 19, 2025

It’s a Cell-Eat-Self World: ULK1, AMPK & mTOR Signaling in Autophagy

If the thought of self-cannibalization is not appealing to you, you may not want to read the next se...
Alexandra Foley May 22, 2024

Interrogating Immunometabolism in the TME Using a Metabolic Checkpoint

Previously considered distinct disciplines, the fields of immunology and metabolism are converging i...
Jianxin Xie, PhD Apr 17, 2024

M6A: A Cell’s Hidden Signal of Gene Regulation Through RNA

Guest author Gina Lee, PhD, is an Assistant Professor of Microbiology and Molecular Genetics at the ...
Gina Lee, PhD Sep 28, 2022

Hypoxia and Its Role in Metabolism

Hypoxia—the deficiency of oxygen in the cellular environment—causes cellular stress and alters norma...
Chris Sumner Jun 8, 2022

Tools for Classifying Cells and Identifying Protein Localization

When do I want to classify cells? Why do I care where a protein localizes? These are actually two di...
Andrea Tu, PhD Jan 26, 2022

Emerging Discoveries in ER-Phagy

Autophagy is a catabolic process for the disposal of cytoplasmic contents that are captured by doubl...
Gary Kasof, PhD Nov 3, 2021

The Role of Metabolism in Disease

Metabolism plays a central role in many diseases, including diabetes, cardiovascular disease, obesit...
Chris Sumner Oct 27, 2021

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