CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology® (CST) where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Lab Expectations listing page

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M6A: A Cell’s Hidden Signal of Gene Regulation

Cells have developed sophisticated regulation mechanisms to ensure proper development and function. ...
Gina Lee, PhD Sep 28, 2022

The Importance of ISG15 in Covid Research

Historically, the ISG15 protein hasn’t been thoroughly investigated by researchers. We know it can f...
Francesco P Feb 9, 2022

Tools for Screening and Quantifying Proteins

Whether your heart is devoted to cardiac research, you’re excited to investigate neurodegenerative d...
Steve M Oct 20, 2021

Tools for Modulating Cells

Cell behavior is a tightly regulated, finely tuned process where various different signals work toge...
Andrea T Oct 13, 2021

Tools for Monitoring Cell State

Have you been wondering how to monitor a cell state or cellular response? From a basic research stan...
Andrea T Oct 6, 2021

Understanding Mitophagy

Mitochondrial health is a complex, carefully regulated process involving pathways that determine mit...
Gary Kasof, PhD Aug 11, 2021

Mechanisms of Cell Death: Ferroptosis

Ferroptosis is a recently described form of programmed cell death with distinct morphological and bi...
Gary Kasof, PhD Jun 2, 2021

Mechanisms of Cell Death: Necrosis & Necroptosis

The thought of necrotic cell death might bring to mind images from an old horror movie, but as with ...
April Lowell, PhD Apr 28, 2021

How Do I Measure Metabolism?

Several different assays can be used by scientists to measure metabolism in a variety of contexts. T...
Chris Sumner Apr 21, 2021

Mechanisms of Cell Death: Pyroptosis

Under the category of necrotic cell death, there are many well-characterized, as well as some newly ...
April Lowell, PhD Apr 7, 2021

The Role of Autophagy and ER Stress in Viral Infection

The regulation of ER stress and autophagy during viral infection is an important factor in the balan...
Gary Kasof, PhD Oct 28, 2020

Cell Process: Which markers can be used to identify cellular senescence?

In response to a variety of environmental factors – like ionizing radiation, exposure to chemotherap...
Tamar A Oct 14, 2020

Cell Process: What role does senescence play in disease?

Cellular senescence occurs when cells cease proliferation and irreversibly exit the cell cycle. Whil...
Tamar A Oct 7, 2020

Cell Process: What role do the telomeres play in senescence?

Senescence is a cellular state during which cells remain metabolically active, but irreversibly with...
Tamar A Sep 16, 2020

Cell Process: How is cellular senescence related to aging?

Senescence, the cessation of cell division and permanent withdrawal from the cell cycle, is a proces...
Tamar A Sep 9, 2020

Cell Process: What signaling pathways are associated with cellular senescence?

Senescence is the irreversible arrest of proliferation in response to a variety of cellular stressor...
Tamar A Aug 26, 2020

PI3K/Akt Signaling Targets Hit Close to Home

The ability of cells to recognize external signal cues (ligands and nutrients) and appropriately res...

Cell Process: What is cell senescence?

Cellular senescence is a state of stable cell cycle arrest under which cells remain metabolically ac...
Tamar A Aug 12, 2020

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