CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Key Epithelial-Mesenchymal Transition (EMT) Markers in Cancer

EMT, or epithelial-mesenchymal transition, is a biological process in which epithelial cells gain th...
Susan Keezer, PhD Jun 4, 2025

Targeting the Tumor Microenvironment: Key Markers of the ECM

In recent years, cancer researchers have started paying closer attention to the extracellular matrix...
Susan Keezer, PhD May 28, 2025

Immunology: What are myeloid cells and how are they identified?

During hematopoiesis, myeloid cells develop from a common myeloid progenitor (CMP) found in the bone...
Rob MacDonald, PhD May 22, 2025

Immunology: What are lymphoid cells and how are they identified?

In humans, hematopoietic stem cells (HSCs) continuously replenish all types of blood cells via a ser...
Amrik Singh, PhD May 21, 2025

Hypoxia and Its Role in Metabolism

Hypoxia—the deficiency of oxygen in the cellular environment—causes cellular stress and alters norma...
Chris Sumner Jun 8, 2022

Xenophagy: What You Eat Can’t Hurt You

Xenophagy provides an important defense against foreign pathogens such as bacteria and viruses by ta...
Gary Kasof, PhD Sep 15, 2021

Antibody Essentials: Important Considerations for Antibody Selection

As a researcher, you know that at a fundamental level, your experiments are geared to ask new questi...
Kenneth Buck, PhD Aug 4, 2021

Antibody Essentials: What Are Polyclonal vs Monoclonal Antibodies?

In this blog series, we are delving into some of the advantages and disadvantages of polyclonal and ...
Kenneth Buck, PhD Jul 28, 2021

Antibody Essentials: How Antibody Technologies Evolved

Since the discovery of antibodies, decades of research and development have spurred technological ad...
Kenneth Buck, PhD Jul 21, 2021

Antibody Essentials Part 2: Antibody Diversity and Classification

Understanding how antibodies are made and the pros and cons of the different types of antibodies is ...
Kenneth Buck, PhD Jul 14, 2021

Antibody Essentials: What Is a Research Antibody?

As a scientist, you probably already appreciate the vital role of antibodies in research. You may al...
Kenneth Buck, PhD Jul 7, 2021

Immunology: Immunophenotyping Basics

Immunophenotyping is a technique that uses antibodies to allow the identification and quantification...
Chris Sumner Jun 30, 2021

Neuroinflammation in Neurodegenerative Diseases

Neuroinflammation is the activation of an immune response in the central nervous system (CNS; brain ...
Chris Sumner Jun 23, 2021

Mechanisms of Cell Death: Ferroptosis

What is ferroptosis? Ferroptosis is an iron-dependent form of programmed cell death with distinct mo...
Gary Kasof, PhD Jun 2, 2021

What is glycolysis and what is its role in metabolism?

Glycolysis and oxidative respiration are the two major metabolic pathways cells employ in order to c...
Chris Sumner May 26, 2021

Neurotransmitters, Receptors, and Transporters

Neurons are central nervous system (CNS) cells that receive and transmit electrochemical signals by ...
Chris Sumner May 19, 2021

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