CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Hypoxia and Its Role in Metabolism

Hypoxia, defined as the deficiency of oxygen in the biotic environment, causes cellular stress and a...
Chris Sumner Jun 8, 2022

Immunology: Which Cells Have a Lymphoid Lineage and How Are They Identified?

In humans, hematopoietic stem cells (HSCs) continuously replenish all types of blood cells via a ser...
Emma E Jan 19, 2022

Tools to Perform Genomic Profiling

Techniques used in genomic profiling have come a long way in the past few decades. Researchers can n...
Curtis Desilets Dec 1, 2021

Xenophagy: What You Eat Can’t Hurt You

Xenophagy provides an important defense against foreign pathogens such as bacteria and viruses by ta...
Gary Kasof, PhD Sep 15, 2021

Antibody Essentials Part 5: Important Considerations for Antibody Selection

As a researcher, you know that at a fundamental level, your experiments are geared to ask new questi...

Antibody Essentials Part 4: Polyclonal vs Monoclonal Antibodies

In this blog series, we are delving into some of the advantages and disadvantages of polyclonal and ...
Kenneth Buck, PhD Jul 28, 2021

Antibody Essentials Part 3: How Antibody Technologies Evolved

Since the discovery of antibodies, decades of research and development have spurred technological ad...

Antibody Essentials Part 2: Antibody Diversity and Classification

Understanding how antibodies are made and the pros and cons of the different types of antibodies is ...
Kenneth Buck, PhD Jul 14, 2021

Antibody Essentials Part 1: Antibody Basics

As a scientist, you probably already appreciate the vital role of antibodies in research. You may al...

Immunology: Immunophenotyping Basics

Immunophenotyping is a technique that uses antibodies to allow the identification and quantification...
Chris Sumner Jun 30, 2021

What is glycolysis and what is its role in metabolism?

Glycolysis and oxidative respiration are the two major metabolic pathways cells employ in order to c...
Chris Sumner May 26, 2021

Mechanisms of Cell Death: Necrosis & Necroptosis

The thought of necrotic cell death might bring to mind images from an old horror movie, but as with ...
April Lowell, PhD Apr 28, 2021

Introduction to Metabolism

Cellular metabolism encompasses all of the chemical processes that occur within cells to maintain ho...
Chris Sumner Feb 3, 2021

What Is Neurodegenerative Disease?

Neurodegeneration is marked by the progressive loss of neuronal function and structure leading to co...
Chris Sumner Jan 20, 2021

B Cell Basics: What a Disease Researcher Needs to Know

Changes in the activation of intracellular signaling networks downstream of B-cell receptors (BCR) l...
Tamar A Nov 18, 2020

T Cell Basics: What a Disease Researcher Needs to Know

T cells are highly specialized lymphocytes that play a critical role in the cell-mediated arm of the...
Tamar A Nov 11, 2020

The Role of Autophagy and ER Stress in Viral Infection

The regulation of ER stress and autophagy during viral infection is an important factor in the balan...
Gary Kasof, PhD Oct 28, 2020

The Role of Cell Death in Viral Infection

The regulation of cell death during viral infection is an important factor in the balance of virus a...
Gary Kasof, PhD Oct 21, 2020

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