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Hypoxia and Its Role in Metabolism

Hypoxia—the deficiency of oxygen in the cellular environment—causes cellular stress and alters norma...
Chris Sumner Jun 8, 2022

Xenophagy: What You Eat Can’t Hurt You

Xenophagy provides an important defense against foreign pathogens such as bacteria and viruses by ta...
Gary Kasof, PhD Sep 15, 2021

Antibody Essentials: What Are Polyclonal vs Monoclonal Antibodies?

In this blog series, we are delving into some of the advantages and disadvantages of polyclonal and ...
Kenneth Buck, PhD Jul 28, 2021

Antibody Essentials: How Antibody Technologies Evolved

Since the discovery of antibodies, decades of research and development have spurred technological ad...
Kenneth Buck, PhD Jul 21, 2021

Antibody Essentials: Antibody Diversity and Classification

Understanding how antibodies are made and the pros and cons of the different types of antibodies is ...
Kenneth Buck, PhD Jul 14, 2021

Antibody Essentials: What Is a Research Antibody?

As a scientist, you probably already appreciate the vital role of antibodies in research. You may al...
Kenneth Buck, PhD Jul 7, 2021

Immunology: Immunophenotyping Using Flow Cytometry or IHC

In the field of immunology and immuno-oncology, immunophenotyping is a technique that uses antibodie...
Chris Sumner Jun 30, 2021

Neuroinflammation in Neurodegenerative Diseases

Neuroinflammation is the activation of an immune response in the central nervous system (CNS; brain ...
Chris Sumner Jun 23, 2021

What is glycolysis and what is its role in metabolism?

Glycolysis and oxidative respiration are the two major metabolic pathways cells employ in order to c...
Chris Sumner May 26, 2021

Neurotransmitters, Receptors, and Transporters

Neurons are central nervous system (CNS) cells that receive and transmit electrochemical signals by ...
Chris Sumner May 19, 2021

Mechanisms of Cell Death: Necrosis & Necroptosis

The thought of necrotic cell death might bring to mind images from an old horror movie, but as with ...
April Lowell, PhD Apr 28, 2021

What is Neurodegeneration?

Neurodegeneration is marked by the progressive loss of neuronal function and structure, leading to c...
Chris Sumner Jan 20, 2021

B Cell Basics: Markers, Signaling Pathways & Immune Outcomes

Changes in the activation of intracellular signaling networks downstream of B-cell receptors (BCR) l...
Tamar Aprahamian, PhD Nov 18, 2020

T Cell Basics: What a Disease Researcher Needs to Know

T cells are highly specialized lymphocytes that play a critical role in the cell-mediated arm of the...
Tamar Aprahamian, PhD Nov 11, 2020

The Role of Autophagy and ER Stress in Viral Infection

The regulation of ER stress and autophagy during viral infection is an important factor in the balan...
Gary Kasof, PhD Oct 28, 2020

The Role of Cell Death in Viral Infection

The regulation of cell death during viral infection is an important factor in the balance of virus a...
Gary Kasof, PhD Oct 21, 2020

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