CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Menin-KMT2A Inhibitors: A Promising Approach to Acute Myeloid Leukemia (AML) Treatment

Accounting for about 80% of adult acute leukemias, acute myeloid leukemia (AML) is an aggressive for...
Homa Rahnamoun, PhD Oct 16, 2024

tRNA Modification by m7G MTase: Understanding its Role in Cancer and Developmental Disorders

Guest blogger Richard I. Gregory, PhD, is a professor at Harvard Medical School and Principal Invest...

M6A: A Cell’s Hidden Signal of Gene Regulation Through RNA

Guest blogger Gina Lee, PhD, is an Assistant Professor of Microbiology and Molecular Genetics at the...
Gina Lee, PhD Sep 28, 2022

Tools to Perform Genomic Profiling

Techniques used in genomic profiling have come a long way in the past few decades. Researchers can n...
Curtis Desilets Dec 1, 2021

Unraveling the Role of G3BPs in the Regulation of Cellular Energetics

In an article recently published by Prentzell et al in Cell, scientists used around 30 different Cel...
Emma E May 12, 2021

How to Prepare a ChIP-seq DNA Library

Chromatin immunoprecipitation sequencing (ChIP-seq) is a flexible and powerful technique used by res...
Tamar Aprahamian, PhD Sep 18, 2019

BAFfling Epigenetic Remodeling in Disease States

The massive amount of DNA in the human body is truly baffling. Stretched end to end, the DNA from a ...
Curtis Desilets Jul 24, 2019

How to Choose Enzymatic or Sonication Protocol for ChIP

Researchers use chromatin immunoprecipitation, or ChIP, to identify and characterize protein-DNA int...
Chris Sumner Jun 26, 2019

Journal Club | The genomic address of bivalent nucleosomes

The activity of genes and their regulatory elements is, in part, governed by their cell type-specifi...
Liana G Apr 26, 2017

How to Validate a Histone Modification Antibody

Antibodies targeted to histone modifications may bind non-specifically to similar, but off-target hi...
Carolyn P Feb 1, 2017

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