CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology® (CST) where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Introducing Versatile CAR Detection Reagents: Anti-CAR Linker mAbs

Chimeric antigen receptor (CAR) T-cell therapy is a revolutionary and rapidly evolving type of adopt...
Amrik Singh, PhD Nov 8, 2022

Therapeutic Approaches for the Treatment of Multiple Myeloma

Multiple myeloma is a cancer of plasma cells that is treatable, but not curable. In this blog, we re...
Andrea T Jul 2, 2022

Novel Therapeutic Approaches for Diffuse Large B Cell Lymphoma

Lymphoma is a cancer of the lymphatic system, a principal part of the body’s immune system. Lymphoma...
Andrea T May 11, 2022

Pancreatic Cancer: Targeting Novel Drivers in the Tumor Microenvironment

  Pancreatic cancer is devastating and difficult to diagnose early. The organ is located deep inside...
Andrea T Apr 27, 2022

Melanoma: Aberrant Signaling Pathways and Therapeutic Approaches

There are three major types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melan...
Andrea T Mar 30, 2022

Emerging Therapeutic Approaches for Prostate Cancer

Approximately 1 in 8 men will be diagnosed with prostate cancer, a disease which accounts for the se...
Andrea T Feb 23, 2022

Immuno-Oncology: Can T Cells Be Re-trained to Attack Cancer?

The human immune system comprises an array of ingenious cellular components and mechanisms that coll...
Tamar A Jun 3, 2020

10 Must-have Markers for Senescence Research

Understanding when and why cell cycle arrest occurs is critical to many fields of research, includin...
Tamar A May 13, 2020

The Guide to the Hallmarks of Cancer Research Targets

If you haven’t heard already, it’s CST’s 20th anniversary. Woohoo! You could say this year is kind o...
Chris S Oct 9, 2019

Hallmarks of Cancer: Genome Instability and Mutation

Not all cancer cells are equal, they evolve in response to selective pressure driven by accumulation...
Chris S Aug 28, 2019

Hallmarks of Cancer: Tumor Promoting Inflammation

Cancer cells hijack inflammatory mechanisms to promote their own growth and survival. During a norma...
Chris S Aug 21, 2019

Hallmarks of Cancer: Activation Invasion and Metastasis

Cancer cells invade local tissue and spread to distant sites via two distinct, but similar processes...
Chris S Jul 17, 2019

Hallmarks of Cancer: Avoiding Immune Destruction

Some cancer cells adapt mechanisms to evade detection and destruction by the host's immune system. O...
Chris S Jun 12, 2019

Who am I: Can a cellular identity crisis lead to cancer progression?

            The process of epithelial-mesenchymal transition (EMT), whereby differentiated epithelia...
Antony W May 29, 2019

Hallmarks of Cancer: Evading Growth Suppressors

Cancer cells resist inhibitory signals that might otherwise stop their growth. The major pathways in...
Chris S May 1, 2019

Hallmarks of Cancer: Enabling Replicative Immortality

Cancer cells can revert to a pre-differentiated, stem-cell-like phenotype, allowing uninhibited cell...
Chris S Apr 17, 2019

Hallmarks of Cancer: Sustaining Proliferative Signaling

Cancer cells stimulate their own growth, which means they become self-sufficient in growth signals, ...
Chris S Apr 3, 2019

Hallmarks of Cancer: Inducing Angiogenesis Energetics

Cancer cells stimulate the growth of blood vessels to supply nutrients to tumors. Angiogenesis is th...
Chris S Mar 20, 2019

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