CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Faster Immuno-Oncology Research with Rapid T Cell Activation & Expansion

The success of immuno-oncology therapeutics has opened the door to novel cancer elimination strategi...
Andrea Tu, PhD Sep 20, 2023

Cancer Immunotherapy Awareness Month: Fueling the Next Scientific Breakthrough

Did you know June is Cancer Immunotherapy Research Awareness Month? This year, we’ll celebrate 10 ye...
Andrea Tu, PhD Jun 21, 2023

AACR 2023 Recap: Immunotherapy, CAR-T Cell Therapy Research Dominate

Last month marked the annual American Association for Cancer Research (AACR 2023) meeting, which gat...
Alexandra Foley May 10, 2023

World Cancer Day: A Global Call to Action

What is World Cancer Day? Most people will either be directly or indirectly affected by a cancer dia...
Alexandra Foley Feb 6, 2023

Faster CAR-T Cell Detection: Flow Cytometry-Validated Anti-CAR Linker mAbs

CST® anti-CAR linker antibodies won The Innovation Award from CiteAb in 2023. Read on to learn why! ...
Amrik Singh, PhD Nov 8, 2022

Therapeutic Approaches for the Treatment of Multiple Myeloma

Multiple myeloma is a cancer of plasma cells that is treatable, but not curable. In this blog, we re...
Andrea Tu, PhD Jul 2, 2022

Targeting TIGIT for Immunotherapy and T Cell Exhaustion

The evolution of solid tumor cancer treatment has historically centered on a tripartite approach tha...
Tamar Aprahamian, PhD Feb 17, 2021

B Cell Basics: What a Disease Researcher Needs to Know

Changes in the activation of intracellular signaling networks downstream of B-cell receptors (BCR) l...
Tamar Aprahamian, PhD Nov 18, 2020

T Cell Basics: What a Disease Researcher Needs to Know

T cells are highly specialized lymphocytes that play a critical role in the cell-mediated arm of the...
Tamar Aprahamian, PhD Nov 11, 2020

Immuno-Oncology: Can T Cells Be Re-trained to Attack Cancer?

The human immune system comprises an array of ingenious cellular components and mechanisms that coll...
Tamar Aprahamian, PhD Jun 3, 2020

Fibrosis: When Wound Healing Turns to Disease

Fibrosis is a disease that is characterized by scarring and hardening of tissues and organs. Fibrosi...
Susan K Mar 25, 2020

Immunotherapy & CAR-T Cells

Our immune system has the ability to detect and fight infectious pathogens. It can also detect when ...
Chris Sumner Jul 10, 2019

More Than a Phenotype: A Guide to Assessing Tumor-infiltrating Immune Cell Types and Functions

Although the rise of cancer immunotherapy may seem meteoric to many, the history goes back over 100 ...
Emily A Feb 6, 2019

Demystifying Antibody Panel Design for Multiplex IHC

In recent years, immune checkpoint proteins in the tumor microenvironment have been under intense st...
Jen Z Oct 10, 2018

Video: Understanding Macrophages in the Tumor Microenvironment

Research Trends in Macrophage Plasticity It’s an exciting time for immuno-oncology research, as pote...
Kenneth Buck, PhD Sep 19, 2018

Targeting B-Cell Maturation Antigen (BCMA) Holds Promise for Multiple Myeloma Cure

Multiple myeloma (MM) is a type of hematopoietic malignancy characterized, in part, by bone pain, an...
Amrik Singh, PhD Aug 8, 2018

GPNMB: A Promising Immunotherapeutic Target for Triple Negative Breast Cancer

The last few years have witnessed several breakthroughs in the immuno-oncology space. Treatments tha...
Amrik Singh, PhD Apr 4, 2018

Immunotherapy: Empowering Nature’s Anti-Tumor Artillery - Part I

Immunotherapy as an anti-neoplastic strategy has gradually claimed the spotlight over the past sever...
Liana G Dec 6, 2017

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