CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

More Than a Phenotype: A Guide to Assessing Tumor-infiltrating Immune Cell Types and Functions

Although the rise of cancer immunotherapy may seem meteoric to many, the history goes back over 100 ...
Emily Alonzo, PhD Feb 6, 2019

Hallmarks of Cancer: Resisting Cell Death

One thing we know about cancer cells: they can resist death. They evade apoptosis, the mechanism tha...
Chris Sumner Jan 23, 2019

Demystifying Antibody Panel Design for Multiplex IHC

In recent years, immune checkpoints in the tumor microenvironment have been under intense study. If ...
Jen Z Oct 10, 2018

Research Trends in Macrophage Plasticity

It’s an exciting time for immuno-oncology research, as potential predictive biomarkers from an expan...
Kenneth Buck, PhD Sep 19, 2018

Targeting B-Cell Maturation Antigen (BCMA) Holds Promise for Multiple Myeloma Treatment

Multiple myeloma (MM) is a type of hematopoietic malignancy characterized, in part, by bone pain, an...
Amrik Singh, PhD Aug 8, 2018

GPNMB: A Promising Immunotherapeutic Target for Triple Negative Breast Cancer

The last few years have witnessed several breakthroughs in the immuno-oncology space. Treatments tha...
Amrik Singh, PhD Apr 4, 2018

CST is the CiteAb 2018 Antibody Company of the Year!

We, as scientists, learn from each success and failure. Sometimes it takes many failures to achieve ...
Chris Sumner Feb 7, 2018

Journal Club: Hippo pathway and intestinal stem cell regeneration

Journal Club: YAP-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and can...

Journal Club | The genomic address of bivalent nucleosomes

The activity of genes and their regulatory elements is, in part, governed by their cell type-specifi...

From Discovery to Diagnostics: Translational Applications of PTM Proteomics

Part 1 and part 2 introduced mass spectrometry-based proteomic methods, like PTMScan® technology, fo...
Claire S Dec 9, 2015

POSTER | Tumor Immunology: Examining the Microenvironment

The immune system is tasked with distinguishing ‘self’ from ‘non-self’. Tumors can, quite often, be ...

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