CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Lab Expectations listing page

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Hallmarks of Cancer: Resisting Cell Death

One thing we know about cancer cells: they can resist death. They evade apoptosis, the mechanism tha...
Chris Sumner Jan 23, 2019

Demystifying Antibody Panel Design for Multiplex IHC

In recent years, immune checkpoint proteins in the tumor microenvironment have been under intense st...
Jen Z Oct 10, 2018

Video: Understanding Macrophages in the Tumor Microenvironment

Research Trends in Macrophage Plasticity It’s an exciting time for immuno-oncology research, as pote...
Kenneth Buck, PhD Sep 19, 2018

Targeting B-Cell Maturation Antigen (BCMA) Holds Promise for Multiple Myeloma Cure

Multiple myeloma (MM) is a type of hematopoietic malignancy characterized, in part, by bone pain, an...
Amrik Singh, PhD Aug 8, 2018

GPNMB: A Promising Immunotherapeutic Target for Triple Negative Breast Cancer

The last few years have witnessed several breakthroughs in the immuno-oncology space. Treatments tha...
Amrik Singh, PhD Apr 4, 2018

CST is the CiteAb 2018 Antibody Company of the Year!

We, as scientists, learn from each success and failure. Sometimes it takes many failures to achieve ...
Chris Sumner Feb 7, 2018

Characterize Myeloid Cell Mediated Immunosuppression in the Tumor Microenvironment Using Multiplex IHC

The clinical validation of immune checkpoint inhibitors as immunotherapeutic agents for a variety of...
Neha G Jan 24, 2018

Immunotherapy: Empowering Nature’s Anti-Tumor Artillery - Part I

Immunotherapy as an anti-neoplastic strategy has gradually claimed the spotlight over the past sever...
Liana G Dec 6, 2017

Webinar | Validation of a Glycosylation-Independent Antibody Against the Cancer Stem Cell Marker CD133

WEBINAR: Validation of a Glycosylation-Independent Antibody Against the Cancer Stem Cell Marker CD13...
Chris Sumner Nov 22, 2017

Journal Club: Hippo pathway and intestinal stem cell regeneration

Journal Club: YAP-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and can...
Liana G Sep 20, 2017

In-depth Characterization of Immune Checkpoints in the Tumor Microenvironment

Characterize Immune Checkpoint Proteins & T Cell Exhaustion Using Multiplex IHC Advances in immu...
Chris Sumner May 3, 2017

Journal Club | The genomic address of bivalent nucleosomes

The activity of genes and their regulatory elements is, in part, governed by their cell type-specifi...
Liana G Apr 26, 2017

From Discovery to Diagnostics: Translational Applications of PTM Proteomics

Part 1 and part 2 introduced mass spectrometry-based proteomic methods, like PTMScan® technology, fo...
Claire S Dec 9, 2015

POSTER | Tumor Immunology: Examining the Microenvironment

The immune system is tasked with distinguishing ‘self’ from ‘non-self’. Tumors can, quite often, be ...

Immunotherapy: Empowering Nature’s Anti-tumor Artillery - Part II

At your last visit we talked about the rapidly rising popularity of cancer immunotherapy and how it ...
Liana G Sep 9, 2015

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