The massive amount of DNA in the human body is truly baffling. Stretched end to end, the DNA from a single somatic cell is about 2 meters in length, doing the same for all the DNA in the average human would reach the end of the solar system and back!
So your experiments and data are funneling you down an inescapable path. You need to show direct gene regulation by your protein of interest. You think to yourself, “Oh, ChIP...”