Responsible Science Podcast: Episode 2 - The Disruptors


Posted by Chris S on May 23, 2018 3:10:00 AM

We're excited to partner with Science: Disrupt to present a five-part podcast exploring what 'Responsible Science' means amidst the reproducibility crisis.

For the second episode of our ‘Responsible Science’ series, we dive deep into the world of startups intent on making science more responsible through new technologies, modern mentalities, and brand new tools.

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Topics: Reproducibility, Science Education

Shipping Temperature and Antibody Performance: You Asked. CST Answers.


Posted by Chris S on May 16, 2018 3:15:00 AM

Here at CST, we frequently get questions about the proper shipping temperature for antibodies. So we thought we would do an interview with an expert on this topic, our very own Seneca Stone who directs our global supply chain operations.

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Topics: Antibody Performance, Q&A

Painless Publication: How to Write a Journal Abstract


Posted by Chris S on May 9, 2018 3:10:00 AM

Have you ever sat frozen at the keyboard, facing the due date for your abstract and asking yourself how you can condense all of this information into 200 words or less? If this scenario resonates with you, rest assured you are not alone. There is a learning curve for writing an effective abstract, and thankfully there are also some tips that will help you get started and finish strong.

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Topics: techniques, Q&A, Career Development, Science Education

#Antibodies Go Social


Posted by Tara W on May 2, 2018 3:15:00 AM

It began with an Instagram pic of a 100 uL tube:

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Topics: Just for fun, Science Education

Responsible Science Podcast: Episode 1 - Overview


Posted by Chris S on Apr 25, 2018 3:10:00 AM

We're excited to partner with Science: Disrupt to present a five-part podcast exploring what 'Responsible Science' means amidst the reproducibility crisis.

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Topics: Reproducility, Science Education

Are you ready to transfer your protein? Wet vs. semi-dry transfer


Posted by Neha G on Apr 18, 2018 3:15:00 AM

 You are all amped up to run a western blot to identify “your favorite protein.” The lysates have been run and proteins separated by SDS-PAGE. Now it’s time to transfer proteins from the gel to the membrane, and you’re sitting wondering….wet or semi-dry?? Or maybe you are better prepared than I was as a graduate student and you already know your next step, in which case you are aware of the pros and cons of wet and semi-dry transfer.

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Topics: Protocols, Western Blot, techniques, Science Education

Still in the Dark: AMD Patients Wait for Answers


Posted by Chris S on Apr 11, 2018 3:15:00 AM

In Mr. D’s sophomore English class, almost no subject was taboo or off limits. Even with our class projects, he encouraged us to pursue topics that truly interested us, and sometimes that meant having to educate Mr. D about something entirely new to him. But if your presentation included stunning visuals, you had to be prepared to paint a word picture. Macular degeneration rendered his otherwise healthy eyes all-but-useless. 

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Topics: Reproducibility, Neurodegeneration, Therapeutics, Immunotherapy

GPNMB: A Promising Immunotherapeutic Target for Triple Negative Breast Cancer


Posted by Amrik S. on Apr 4, 2018 3:00:00 AM

The last few years have witnessed several breakthroughs in the immuno-oncology space. Treatments that harness the body’s immune system to fight cancer have transitioned from speculation to offering endless possibilities for drug discovery. Of these treatments, therapeutic monoclonal antibodies are positioned at the forefront of the immunotherapy revolution, and the FDA has approved several of these monoclonal antibodies to treat cancer.

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Topics: Cancer Immunology, Cancer Research, Therapeutics, Medicine, antibody-drug conjugates, Immunotherapy

Webinar | Proteomics profiling of post-translational modifications in early drug discovery


Posted by Chris S on Mar 28, 2018 3:15:00 AM

Advances in mass spectrometry instrumentation and sample handling methods have propelled proteomics and extended its utility for both basic biology and early drug development. Changes in protein abundance and post-translational modification state often reflect the activity of a novel therapeutic agent as well as the sensitivity/resistance of a biological system to treatment.

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Topics: Proteomics, Webinars

Have You Ever Wondered...How Do I Choose a Loading Control?


Posted by Chris S on Mar 21, 2018 6:15:00 AM

For those who wish to bring a measure of rationality to the western blot data in the literature, loading controls can induce a fair amount of hand wringing. There are some obvious criteria. First, the protein level of the loading control must not be altered by experimental conditions. Second, the molecular weight of the control must be different from the protein of interest. Third, and most importantly, the signal detected for both the loading control and the protein of interest must be in a linear range, otherwise you’ll find yourself with burnt-out bands that you’ll be unable to quantify. 

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Topics: Western Blot

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