2020 CiteAb Awards


Posted by Chris S on Mar 11, 2020 7:53:58 AM

We’re honored to win two CiteAb awards in 2020: Antibody Supplier of the Decade and Antibody Supplier Succeeding in Alzheimer’s Research. CST was also highly commended as an ELISA Kit Supplier to Watch in 2020. It’s always nice to be recognized for your work. In this case, it’s especially sweet because both efforts are near and dear to our hearts.

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Topics: Antibody Performance

Introduction to the Hallmarks of Antibody Validation


Posted by Chris S on Jan 15, 2020 3:00:00 AM

Antibodies are essential reagents that support all levels of scientific research. Used in a multitude of applications to identify, quantify, and isolate specific target biomolecules, they have recently become the focus of intense scrutiny for their contribution to the ongoing reproducibility crisis.

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Topics: Antibody Performance, Antibody Validation

Coming to Lab Expectations in 2020


Posted by Chris S on Jan 1, 2020 3:15:00 AM

            The start of a new year is always a crazy time. There’s plenty to look back on and celebrate, things to anticipate, and of course there are opportunities for improvement. What do we look forward to in 2020? We’re about to celebrate our 5th blog anniversary! It’s hard to believe that Lab Expectations is five years old.

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Topics: Science Education

4 Situations Where Flow Cytometry Might Be More Useful Than Western Blotting


Posted by Chris S on Dec 4, 2019 3:00:00 AM

Western blotting is used to detect proteins and analyze their expression using antibodies, but it does have its limitations. Flow cytometry also employs antibodies, but it uses fluorescence to detect and analyze protein expression on a cell-by-cell basis.

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Topics: Western Blot, Flow, techniques

Critical Considerations for Optimizing Imaging Mass Cytometry


Posted by Chris S on Nov 20, 2019 3:15:00 AM

Understanding the microenvironment of disease is critical for the success of targeted therapies. For years, the complex landscape of the tumor microenvironment could only be studied in single-cell snapshots by flow cytometry or limited tissue staining. Advanced multiplexing technologies such as Imaging Mass Cytometry™ (IMC™) now enable the imaging of up to 40 protein markers on both the cellular and tissue level.

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Topics: IHC

Behind the Antibodies - Interview with a Development Scientist


Posted by Chris S on Oct 16, 2019 3:15:00 AM

Have you ever wondered about the minds behind our antibodies? We talk a lot about validation, specificity, sensitivity, and reproducibility. All of that is very important, but that doesn't tell you much about who developed it.

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Topics: Antibody Performance, Primary Antibodies, Antibody Validation

The Guide to the Hallmarks of Cancer Research Targets


Posted by Chris S on Oct 9, 2019 3:15:00 AM

If you haven’t heard already, it’s CST’s 20th anniversary. Woohoo! You could say this year is kind of a big deal for us. We have a lot to celebrate. However, once we started listing the successes over the years, we realized that we are most proud of what you – the researchers worldwide – have accomplished using our reagents. After all, we don’t live in a vacuum. We exist to serve you and enable important discoveries and the development of cures.

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Topics: Cell Biology, Cancer Research

20 Years of Research, Reagents, and Lasting Relationships


Posted by Chris S on Oct 1, 2019 3:10:00 AM

Today marks 20 years of impact in scientific research and community support. We haven't done this alone — you’ve inspired us to think bigger and tackle greater challenges— we’ve Created Something Together. Thank you for standing with us.

 
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Topics: Corporate Social Responsibility

Hallmarks of Cancer: Genome Instability and Mutation


Posted by Chris S on Aug 28, 2019 3:10:00 AM

Not all cancer cells are equal, they evolve in response to selective pressure driven by accumulation of mutations. Cancer cells have to out-compete nearby cells for nutrients and other resources, avoid immune cell attack, and suppress apoptotic self-destruction.

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Topics: Cancer Immunology, Cell Biology

Hallmarks of Cancer: Tumor Promoting Inflammation


Posted by Chris S on Aug 21, 2019 3:15:00 AM

Cancer cells hijack inflammatory mechanisms to promote their own growth and survival. During a normal inflammatory response by the innate and adaptive immune system, immune cells carry out their designated task of engulfing and/or destroying foreign invaders.

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Topics: Cell Biology, Cancer Research

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