The Role of Autophagy and ER Stress in Viral Infection


Posted by Gary K. on Oct 28, 2020 3:00:00 AM

The regulation of ER stress and autophagy during viral infection is an important factor in the balance of virus and host survival. In this series, we look at pathways that are regulated through cellular responses to virus, as well as in response to virally encoded proteins. Infection of the coronaviruses SARS-CoV and SARS-CoV-2 causes severe lung injury with extensive damages to alveolar and bronchial epithelial cells, and produces extra-pulmonary damage.

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Topics: Cell Biology

The Role of Cell Death in Viral Infection


Posted by Gary K. on Oct 21, 2020 3:15:00 AM

The regulation of cell death during viral infection is an important factor in the balance of virus and host survival. In this series, we look at pathways that are regulated through cellular responses to virus, as well as in response to virally encoded proteins. Infection of the coronaviruses SARS-CoV and SARS-CoV-2 causes severe lung injury with extensive damages to alveolar and bronchial epithelial cells, and produces extra-pulmonary damage.

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Topics: Cell Biology

Necroptosis and Pyroptosis Add to Our Understanding of Apoptotic Cell Death


Posted by Gary K. on Mar 13, 2019 3:05:00 AM

Over the last 50 years laboratories have been able to demonstrate through experimentation the processes contributing to cell death. Early discoveries focused on morphological features of cell death and classifications into apoptosis and necrosis. Since then, there have been many more discoveries regarding the programmed cellular pathways contributing to apoptosis.

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Topics: Cell Biology

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