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The official blog of Cell Signaling Technology, where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Selecting Matched Antibody Pairs that Keep Assay Development on Track

Since the invention of the enzyme‑linked immunosorbent assay (ELISA) more than 50 years ago, the ori...
Alexandra Foley Apr 29, 2026

ELISA Reproducibility: How CST Validates Lot-to-Lot Consistency

Over the past eight years working as a Product Scientist at CST, a big part of my role has been to t...
Emily Estabrook Aug 27, 2025

Setting the Standard: CST's Commitment to Antibody Validation Through YCharOS

Within the complex landscape of biomedical research, antibodies stand as critical tools for scientif...

Watch Your Bax: How a Faulty Antibody May Have Cost Millions in Flawed Research

Science is a collaborative effort—a joint pursuit where each discovery builds on the foundation buil...
Alexandra Foley Apr 9, 2025

Antibody Validation: Orthogonal Strategy

An orthogonal strategy for antibody validation involves cross-referencing antibody-based results wit...
Alexandra Foley Mar 27, 2025

Do You Trust Your Research Antibody?

There’s no getting around it: Selecting the right antibody can make or break your experiment. If the...
Alexandra Foley Feb 26, 2025

900 Antibodies & Counting: How Are CST Antibodies Validated for Simple Western Technology?

Since 2022, Cell Signaling Technology (CST) and Bio-Techne have been working together to bring best-...
Chris LaBreck, PhD Oct 23, 2024

How to Detect the ADP-Ribosylation PTM Using a Monoclonal Antibody

Protein adenosine diphosphate, or ADP-ribosylation, is a fascinating post-translational modification...

Validated Antibodies for p-Tau217: A Blood-Based Alzheimer’s Disease Biomarker

With Alzheimer’s disease (AD) set to affect more than 7.1 million people over 65 worldwide by 2025, ...
Arica Aiello Aug 14, 2024

5 Reasons to Choose a Conjugation Service Over an Antibody Labeling Kit

The need for antibody conjugation is on the rise due to the increased use of multiplexing. Not only ...
Alexandra Foley Mar 6, 2024

Antibody Validation for IHC: Finding a Claudin-6 Monoclonal Antibody Clone

Developing research antibodies is an extensive process that takes advantage of an animal’s adaptive ...
Alexandra Foley Nov 15, 2023

Increase Your Experimental Success with CUT&RUN-Validated Antibodies

CUT&RUN delivers the power of chromatin immunoprecipitation (ChIP) or ChIP-sequencing (ChIP-seq)...
Christopher Fry, PhD Oct 26, 2022

Comparing Antibody Concentrations & Performance; CST Antibody Details You May Not Know

When purchasing antibodies from Cell Signaling Technology (CST), you may notice that we typically re...
Josh Nathan Oct 12, 2022

Tools to Confirm Antibody Specificity

You want to generate accurate results. You’ve planned out your experiment, accounting for all necess...
Chris Sumner Mar 2, 2022

Antibody Essentials: Important Considerations for Antibody Selection

As a researcher, your experiments are designed to ask new questions and pursue scientific knowledge ...
Kenneth Buck, PhD Aug 4, 2021

What is a Recombinant Antibody and Why is it Important?

Recombinant antibodies offer several key advantages compared to traditional antibodies. These includ...

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