CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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IHC-Validated p16 INK4A Antibody: Jump-Start Your Senescence Research

Cell cycle regulation is vital to maintain tissue homeostasis and to prevent sustained proliferative...
Andrea Tu, PhD Apr 19, 2023

tRNA Modification by m7G MTase: Understanding its Role in Cancer and Developmental Disorders

Guest author Richard I. Gregory, PhD, is a professor at Harvard Medical School and Principal Investi...

World Cancer Day: A Global Call to Action

Most people will either be directly or indirectly affected by a cancer diagnosis at some point in th...
Alexandra Foley Feb 6, 2023

The Biopharma Trends to Watch in 2023, According to CST Scientists

Technological innovation leads to a deeper understanding of the natural world and the underlying cau...
Alexandra Foley Jan 18, 2023

CAR T Cell Detection: Anti-CAR Linker Antibodies for Whitlow/218 & G4S

CST® anti-CAR linker antibodies won The Innovation Award from CiteAb in 2023. Read on to learn why! ...
Amrik Singh, PhD Nov 8, 2022

Therapeutic Approaches for the Treatment of Multiple Myeloma

Multiple myeloma is a cancer of plasma cells that is treatable, but not curable. In this blog, we re...
Andrea Tu, PhD Jul 2, 2022

Hypoxia and Its Role in Metabolism

Hypoxia—the deficiency of oxygen in the cellular environment—causes cellular stress and alters norma...
Chris Sumner Jun 8, 2022

Novel Therapeutic Approaches for Diffuse Large B-Cell Lymphoma

Lymphoma is a cancer of the lymphatic system, a principal part of the body’s immune system. Lymphoma...
Andrea Tu, PhD May 11, 2022

Pancreatic Cancer: Targeting Novel Drivers in the Tumor Microenvironment

Pancreatic cancer is devastating and difficult to diagnose early. The organ is located deep inside t...
Andrea Tu, PhD Apr 27, 2022

Melanoma: Aberrant Signaling Pathways and Therapeutic Approaches

There are three major types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melan...
Andrea Tu, PhD Mar 30, 2022

Emerging Therapeutic Approaches for Prostate Cancer

Approximately one in eight men will be diagnosed with prostate cancer during their lifetime, making ...
Andrea Tu, PhD Feb 23, 2022

Cancer Biomarker Antibody Selection for IHC

What are cancer biomarkers? Biomarkers are naturally occurring molecules that can be used as indicat...

The Role of Metabolism in Cancer

Alterations in the cellular metabolism of malignant cells have long been a central focus of cancer r...
Chris Sumner Mar 24, 2021

Targeting TIGIT for Cancer Immunotherapy & T Cell Exhaustion

The evolution of solid tumor cancer treatment has historically centered on a tripartite approach tha...
Tamar Aprahamian, PhD Feb 17, 2021

T Cell Basics: What a Disease Researcher Needs to Know

T cells are highly specialized lymphocytes that play a critical role in the cell-mediated arm of the...
Tamar Aprahamian, PhD Nov 11, 2020

How Can T Cells Be Re-trained to Attack Cancer?

The human immune system comprises an array of ingenious cellular components and mechanisms that coll...
Tamar Aprahamian, PhD Jun 3, 2020

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