CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Immunology: What are myeloid cells and how are they identified?

During hematopoiesis, myeloid cells develop from a common myeloid progenitor (CMP) found in the bone...
Rob MacDonald, PhD May 21, 2025

Immunology: What are lymphoid cells and how are they identified?

In humans, hematopoietic stem cells (HSCs) continuously replenish all types of blood cells via a ser...
Amrik Singh, PhD May 21, 2025

Your Antibody Toolbox for Neurodegenerative Disease Biomarker Research with Biofluid Samples

Neurodegenerative disease research is in serious need of reliable biomarkers—whether to develop meth...
Supriya Singh, PhD May 14, 2025

Setting the Standard: CST's Commitment to Antibody Validation Through YCharOS

Within the complex landscape of biomedical research, antibodies stand as critical tools for scientif...

Do mRNA and protein levels correlate? Not necessarily.

To what extent does mRNA dictate cellular protein levels? It depends. For decades, scientists have u...
Tyler Levy Apr 23, 2025

Spatial Insights for CAR-Engineered Cells in Solid Tumors: Antibody-Based CAR Detection Method

Cell Signaling Technology provides products and services are for research use only and not for use i...
Amrik Singh, PhD Apr 16, 2025

Watch Your Bax: How a Faulty Antibody May Have Cost Millions in Flawed Research

Science is a collaborative effort—a joint pursuit where each discovery builds on the foundation buil...
Alexandra Foley Apr 9, 2025

Reforest The Tropics: Turning Carbon into Canopies

In honor of Earth Month 2025, we’re giving the (forest) floor to Reforest The Tropics (RTT), a pione...

Antibody Validation Essentials: Orthogonal Strategy

An orthogonal strategy for antibody validation involves cross-referencing antibody-based results wit...
Alexandra Foley Mar 27, 2025

Research Round-Up: CST® Anti-CAR Linker Antibodies in the Literature

As chimeric antigen receptor (CAR) cell therapies for the treatment of solid tumors, hematologic mal...
Alexandra Foley Mar 5, 2025

Do You Trust Your Research Antibody?

There’s no getting around it: Selecting the right antibody can make or break your experiment. If the...
Alexandra Foley Feb 26, 2025

Why is combining single cell RNA and intracellular signaling data difficult?

What if you could measure RNA, determine cell type, and detect intracellular signaling, all in a sin...
Alexandra Foley Feb 19, 2025

Does It Really Work? How InTraSeq™ Integrates Transcriptomic, Proteomic, & Intracellular Interaction Data

The ability to detect intracellular proteins alongside RNA has long been a challenge in single cell ...
Alexandra Foley Feb 12, 2025

Meet the Winners of the 5th Annual Rising Black Scientists Awards

We’re thrilled to announce the winners of the 5th annual Rising Black Scientists Awards! Since 2020,...
Alexandra Foley Feb 6, 2025

3x the Data, 3x the Insights: What's the difference between DIA & DDA proteomics?

As biotech companies continue to leverage proteomics profiling for critical research such as biomark...
Jeffrey Silva, PhD Jan 31, 2025

Microglial Activation Antibody Toolkit: High-Content Methods to Study TREM2 Signaling

Selecting antibodies for molecular signaling research in neurodegeneration is a complex and nuanced ...
Ginny Bain, PhD Jan 8, 2025

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