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Hallmarks of Cancer: Tumor-Promoting Inflammation

Inflammation can play different roles in the context of cancer. Short-lived inflammatory signaling c...
Rob MacDonald, PhDMar 25, 2026

Reliable Data Normalization for CUT&RUN and CUT&Tag with Whole Workflow Spike-In Controls

If you use CUT&RUN or CUT&Tag to map histone modifications, DNA methylation, transcription f...
Alexandra FoleyMar 18, 2026

Fluorescent Staining with Multiple Antibodies: Direct vs Indirect Methods for Multiplex Immunofluorescence

Direct and indirect multiplex immunofluorescence (mIF) offer straightforward ways to explore spatial...
Alexandra FoleyMar 11, 2026

Antibody Compatibility Trifecta: Choosing a Multiplexing Strategy for Reliable Spatial Biology Insights

Spatially resolved multiplex detection links cellular phenotype and function to tissue architecture,...
Alexandra FoleyMar 4, 2026

Choosing the Right Ubiquitination Assay for Targeted Protein Degradation Research

In targeted protein degradation (TPD) drug discovery, confirming target ubiquitination is a pivotal ...
Gary Kasof, PhDFeb 25, 2026

Unlocking the Power of Ubiquitin: The Science Behind Targeted Protein Degradation

Ubiquitin is a small but powerful protein that functions in nearly all cellular signaling pathways a...
Gary Kasof, PhDFeb 18, 2026

Hallmarks of Cancer: Evading Growth Suppressors

Imagine driving down the highway with no brakes. That is essentially what happens when tumor cells l...
Gary Kasof, PhDFeb 11, 2026

Unlocking Protein-Level Insights in CAR-T Single Cell Analysis

Single cell RNA sequencing (scRNA-seq) has been a powerful tool to uncover heterogeneity in T cell p...
Majd Ariss, PhDFeb 4, 2026

Hallmarks of Cancer: Sustaining Proliferative Signaling

Cancer thrives by keeping cell proliferation stuck in the “on” position. Normally, cells wait for th...
Julian Arthur, PhDJan 21, 2026

Hallmarks of Cancer: Senescent Cells

Senescence, a stable and generally irreversible state of cell cycle arrest, is a double-edged sword ...
Susan Keezer, PhDJan 14, 2026

More Than a Phenotype: Assessing Tumor-Infiltrating Immune Cell Type & Function

Although the rise of cancer immunotherapy may seem meteoric to many, the history actually stretches ...
Emily Alonzo, PhDJan 7, 2026

Hallmarks of Cancer: Resisting Cell Death

One of the defining characteristics of cancer cells is their ability to avoid programmed death—espec...
Gary Kasof, PhDDec 17, 2025

Designing Multiplex IF Experiments for Neuroscience Research with Chimeric Antibodies

Host-based multiplex immunofluorescence (IF) of fixed frozen brain tissue is a powerful approach for...

Hallmarks of Cancer: Nonmutational Epigenetic Reprogramming

Nonmutational epigenetic reprogramming is a defining characteristic of cancer, whereby tumor cells a...
Curtis DesiletsNov 5, 2025

CiteAb Top 100: The Top-Ranked Recombinant Antibodies & Discovery Reagents

Each year, the CiteAb Top 100 Antibodies report highlights the reagents cited most frequently in pub...
Alexandra FoleyOct 31, 2025

Hallmarks of Cancer: Unlocking Phenotypic Plasticity

In 2022, an update was made to the Hallmarks of Cancer framework to expand beyond the eight hallmark...
Antony Wood, PhDOct 22, 2025

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