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Research Round-Up: CST Anti-CAR Linker Antibodies in the Literature

As chimeric antigen receptor (CAR) cell therapies for the treatment of solid tumors, hematologic mal...
Alexandra Foley Jun 2, 2026

Hallmarks of Cancer: Activating Invasion and Metastasis

How do tumors metastasize and spread? In most cancers, this happens through a metastasis cascade dur...
Jing Li, PhD Apr 8, 2026

Hallmarks of Cancer: Tumor-Promoting Inflammation

Inflammation can play different roles in the context of cancer. Short-lived inflammatory signaling c...
Rob MacDonald, PhD Mar 25, 2026

Hallmarks of Cancer: Evading Growth Suppressors

Imagine driving down the highway with no brakes. That is essentially what happens when tumor cells l...
Gary Kasof, PhD Feb 11, 2026

Hallmarks of Cancer: Sustaining Proliferative Signaling

Cancer thrives by keeping cell proliferation stuck in the “on” position. Normally, cells wait for th...
Julian Arthur, PhD Jan 21, 2026

Hallmarks of Cancer: Senescent Cells

Senescence, a stable and generally irreversible state of cell cycle arrest, is a double-edged sword ...
Susan Keezer, PhD Jan 14, 2026

Hallmarks of Cancer: Resisting Cell Death

One of the defining characteristics of cancer cells is their ability to avoid programmed death—espec...
Gary Kasof, PhD Dec 17, 2025

Hallmarks of Cancer: Nonmutational Epigenetic Reprogramming

Nonmutational epigenetic reprogramming is a defining characteristic of cancer, whereby tumor cells a...
Curtis Desilets Nov 5, 2025

Hallmarks of Cancer: Unlocking Phenotypic Plasticity

In 2022, an update was made to the Hallmarks of Cancer framework to expand beyond the eight hallmark...
Antony Wood, PhD Oct 22, 2025

Hallmarks of Cancer: Inducing or Accessing Vasculature (Angiogenesis)

Imagine a rapidly growing city—it needs roads, plumbing, and power lines to thrive. So too, do tumor...
Susan Kane, PhD Oct 8, 2025

Hallmarks of Cancer: Deregulating Cellular Metabolism

Cancer cells have a high demand for biomass—cellular components such as proteins, nucleic acids, and...
Jianxin Xie, PhD Sep 17, 2025

Hallmarks of Cancer: Genome Instability and Mutation

Genetic alterations are a fundamental characteristic of cancer. When DNA mutations and chromosomal r...
Susan Keezer, PhD Aug 20, 2025

Hallmarks of Cancer: Avoiding Immune Destruction

This blog explores the mechanisms, pathways, and proteins involved in one of the Hallmarks of Cancer...
Emily Alonzo, PhD Aug 13, 2025

Key Epithelial-Mesenchymal Transition (EMT) Markers in Cancer

EMT, or epithelial-mesenchymal transition, is a biological process in which epithelial cells gain th...
Susan Keezer, PhD Jun 4, 2025

Targeting the Tumor Microenvironment: Key Markers of the Extracellular Matrix (ECM)

In recent years, cancer researchers have started paying closer attention to the extracellular matrix...
Susan Keezer, PhD May 28, 2025

Menin-KMT2A Inhibitors: A Promising Approach to Acute Myeloid Leukemia (AML) Treatment

Accounting for about 80% of adult acute leukemias, acute myeloid leukemia (AML) is an aggressive for...
Homa Rahnamoun, PhD Oct 16, 2024

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