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Quality Over Quantity: The Case for the Mid-Plex in Spatial Biology

Nature dedicated an entire issue in 2024 to declaring its Method of the Year: Spatial Proteomics.1 B...
Kelsey Goldman Jul 29, 2026

Unlock the Missing Marker: Three Ways to Expand Your Multiplex IHC Panel

If you’re running complex multiplex IHC on precious FFPE samples, you already know the tradeoff: eve...
Kelsey Goldman May 20, 2026

Fluorescent Staining with Multiple Antibodies: Direct vs Indirect Methods for Multiplex Immunofluorescence

Direct and indirect multiplex immunofluorescence (mIF) offer straightforward ways to explore spatial...
Alexandra Foley Mar 11, 2026

Antibody Compatibility Trifecta: Choosing a Multiplexing Strategy for Reliable Spatial Biology Insights

Spatially resolved multiplex detection links cellular phenotype and function to tissue architecture,...
Alexandra Foley Mar 4, 2026

More Than a Phenotype: Assessing Tumor-Infiltrating Immune Cell Type & Function

Although the rise of cancer immunotherapy may seem meteoric to many, the history actually stretches ...
Emily Alonzo, PhD Jan 7, 2026

Designing Multiplex IF Experiments for Neuroscience Research with Chimeric Antibodies

Host-based multiplex immunofluorescence (IF) of fixed frozen brain tissue is a powerful approach for...

Anything but Rabbit: Why Multiplex with Chimeric Antibodies?

It’s a refrain you’ve likely said before: “Give me anything but rabbit!” While rabbit antibodies are...
Supriya Singh, PhD Oct 1, 2025

Multiplexed Methods for Studying the Spatial Biology of the Brain

Cases of neurodegeneration and dementia are predicted to rise with the aging population, yet conditi...
Richard Cho, PhD Aug 7, 2024

CST® Antibodies Validated on the Leica Microsystems Cell DIVE Multiplexed Imaging Solution

True innovation comes from collaboration–from bringing experts together to create techniques and too...
Alexandra Foley Mar 15, 2023

Strategies for Successful Multiplex IF Experiments Using Conjugated Antibodies

One of the benefits of working with immunofluorescent (IF) analysis is the ability to compare multip...
Ginny Bain, PhD Apr 6, 2022

Multiplexing the Brain: A Galaxy of Possibilities

The average human brain contains over 100 billion cells, which is nearly the same number as there ar...
Richard Cho, PhD Dec 15, 2021

Imaging Mass Cytometry: Endless Possibilities to Understand the Microenvironment of Disease

Understanding the microenvironment of disease is critical. Targeted cancer therapies may not be effe...

Demystifying Antibody Panel Design for Multiplex IHC

In recent years, immune checkpoints in the tumor microenvironment have been under intense study. If ...
Jen Z Oct 10, 2018

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