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AACR 2024 Highlights: The Era of Data and Omics Has Arrived

Spatial biology, cell therapy, targeted protein degradation, omics, and large-scale computational an...
Alexandra Foley Apr 24, 2024

Breast Cancer: Understanding BRCA Mutations & PARP Inhibitor Resistance

Each year, approximately 13% of all women in the US and 25% of all women globally will feel their he...
Andrea Tu, PhD Oct 23, 2023

High-Throughput 3D Assay Methods: Analysis of TGF-β Signaling

Spheroids and related three-dimensional (3D) cell models are rapidly gaining popularity among resear...
Alexandra Foley Aug 16, 2023

Something to YAP About! Progress Targeting YAP/TAZ-TEAD Signaling in Cancer Research

YAP and its paralog TAZ (WWTR1), often referred to collectively as YAP/TAZ, are transcriptional co-a...
Antony Wood, PhD May 31, 2023

IHC-Validated p16INK4A Antibody: Jump-Start Your Senescence Research

p16INK4A has become a widely used marker for identifying senescent cells in tissue, yet interpreting...
Andrea Tu, PhD Apr 19, 2023

tRNA Modification by m7G MTase: Understanding its Role in Cancer and Developmental Disorders

Guest author Richard I. Gregory, PhD, is a professor at Harvard Medical School and Principal Investi...

World Cancer Day: A Global Call to Action

Most people will either be directly or indirectly affected by a cancer diagnosis at some point in th...
Alexandra Foley Feb 6, 2023

Hypoxia and Its Role in Metabolism

Hypoxia—the deficiency of oxygen in the cellular environment—causes cellular stress and alters norma...
Chris Sumner Jun 8, 2022

Novel Therapeutic Approaches for Diffuse Large B-Cell Lymphoma

Lymphoma is a cancer of the lymphatic system, a principal part of the body’s immune system. Lymphoma...
Andrea Tu, PhD May 11, 2022

Pancreatic Cancer: Targeting Novel Drivers in the Tumor Microenvironment

Pancreatic cancer is devastating and difficult to diagnose early. The organ is located deep inside t...
Andrea Tu, PhD Apr 27, 2022

Melanoma: Aberrant Signaling Pathways and Therapeutic Approaches

There are three major types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melan...
Andrea Tu, PhD Mar 30, 2022

Emerging Therapeutic Approaches for Prostate Cancer

Approximately one in eight men will be diagnosed with prostate cancer during their lifetime, making ...
Andrea Tu, PhD Feb 23, 2022

The Role of Metabolism in Disease

Metabolism plays a central role in many diseases, including diabetes, cardiovascular disease, obesit...
Chris Sumner Oct 27, 2021

Cancer Biomarker Antibody Selection for IHC

What are cancer biomarkers? Biomarkers are naturally occurring molecules that can be used as indicat...

The Role of Metabolism in Cancer

Alterations in the cellular metabolism of malignant cells have long been a central focus of cancer r...
Chris Sumner Mar 24, 2021

Fibrosis: When Wound Healing Turns to Disease

Fibrosis is a disease that is characterized by scarring and hardening of tissues and organs. Fibrosi...
Susan Keezer, PhD Mar 25, 2020

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