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Menin-KMT2A Inhibitors: A Promising Approach to Acute Myeloid Leukemia (AML) Treatment

Accounting for about 80% of adult acute leukemias, acute myeloid leukemia (AML) is an aggressive for...
Homa Rahnamoun, PhD Oct 16, 2024

Breast Cancer: Understanding BRCA Mutations & PARP Inhibitor Resistance

Each year, approximately 13% of all women in the US and 25% of all women globally will feel their he...
Andrea Tu, PhD Oct 23, 2023

Cancer Immunotherapy Awareness Month: Fueling the Next Scientific Breakthrough

Did you know June is Cancer Immunotherapy Research Awareness Month? This year, we’ll celebrate 10 ye...
Andrea Tu, PhD Jun 21, 2023

AD/PD 2023: Therapeutics, Diagnostics & Mechanisms Linked to a Classic Alzheimer’s Disease Theory

The amyloid cascade hypothesis1, a theory initially proposed over 30 years ago, continues to be the ...
Jordan Hirschfeld Jun 7, 2023

Something to YAP About! Progress Targeting YAP/TAZ-TEAD Signaling in Cancer Research

YAP and its paralog TAZ (WWTR1), often referred to collectively as YAP/TAZ, are transcriptional co-a...
Antony Wood, PhD May 31, 2023

Therapeutic Approaches for the Treatment of Multiple Myeloma

Multiple myeloma is a cancer of plasma cells that is treatable, but not curable. In this blog, we re...
Andrea Tu, PhD Jul 2, 2022

Novel Therapeutic Approaches for Diffuse Large B-Cell Lymphoma

Lymphoma is a cancer of the lymphatic system, a principal part of the body’s immune system. Lymphoma...
Andrea Tu, PhD May 11, 2022

Pancreatic Cancer: Targeting Novel Drivers in the Tumor Microenvironment

Pancreatic cancer is devastating and difficult to diagnose early. The organ is located deep inside t...
Andrea Tu, PhD Apr 27, 2022

Melanoma: Aberrant Signaling Pathways and Therapeutic Approaches

There are three major types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melan...
Andrea Tu, PhD Mar 30, 2022

Emerging Therapeutic Approaches for Prostate Cancer

Approximately one in eight men will be diagnosed with prostate cancer during their lifetime, making ...
Andrea Tu, PhD Feb 23, 2022

Targeting TIGIT for Cancer Immunotherapy & T Cell Exhaustion

The evolution of solid tumor cancer treatment has historically centered on a tripartite approach tha...
Tamar Aprahamian, PhD Feb 17, 2021

GPNMB: A Promising Immunotherapeutic Target for Triple Negative Breast Cancer

The last few years have witnessed several breakthroughs in the immuno-oncology space. Treatments tha...
Amrik Singh, PhD Apr 4, 2018

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