CST BLOG

The official blog of Cell Signaling Technology, where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Antibody Essentials: Important Considerations for Antibody Selection

As a researcher, your experiments are designed to ask new questions and pursue scientific knowledge ...
Kenneth Buck, PhD Aug 4, 2021

Antibody Essentials: What Are Polyclonal vs Monoclonal Antibodies?

In this blog series, we are delving into some of the advantages and disadvantages of polyclonal and ...
Kenneth Buck, PhD Jul 28, 2021

Antibody Essentials: How Antibody Technologies Evolved

Since the discovery of antibodies, decades of research and development have spurred technological ad...
Kenneth Buck, PhD Jul 21, 2021

Antibody Essentials: Antibody Diversity and Classification

Understanding how antibodies are made and the pros and cons of the different types of antibodies is ...
Kenneth Buck, PhD Jul 14, 2021

Antibody Essentials: What Is a Research Antibody?

As a scientist, you probably already appreciate the vital role of antibodies in research. You may al...
Kenneth Buck, PhD Jul 7, 2021

Immunology: Immunophenotyping Using Flow Cytometry or IHC

In the field of immunology and immuno-oncology, immunophenotyping is a technique that uses antibodie...
Chris Sumner Jun 30, 2021

Neuroinflammation in Neurodegenerative Diseases

Neuroinflammation is the activation of an immune response in the central nervous system (CNS; brain ...
Chris Sumner Jun 23, 2021

Autophagy: Taking Out the Cellular Trash Has Widespread Therapeutic Implications

The term “autophagy” introduced by the biochemist Christian de Duve in 1963 is derived from the Gree...
Gary Kasof, PhD Jun 16, 2021

Cancer Biomarker Antibody Selection for IHC

What are cancer biomarkers? Biomarkers are naturally occurring molecules that can be used as indicat...

What is glycolysis and what is its role in metabolism?

Glycolysis and oxidative respiration are the two major metabolic pathways cells employ in order to c...
Chris Sumner May 26, 2021

Neurotransmitters, Receptors, and Transporters

Neurons are central nervous system (CNS) cells that receive and transmit electrochemical signals by ...
Chris Sumner May 19, 2021

Unraveling the Role of G3BPs in the Regulation of Cellular Energetics

In an article published by Prentzell et al in Cell, scientists used around 30 different CST antibodi...

Mechanisms of Cell Death: Necrosis & Necroptosis

The thought of necrotic cell death might bring to mind images from an old horror movie, but as with ...
April Lowell, PhD Apr 28, 2021

Which assays can be used to measure metabolism?

Several different assays can be used to measure metabolism in a variety of contexts. These include m...
Chris Sumner Apr 21, 2021

Mechanisms of Cell Death: Pyroptosis

Under the category of necrotic cell death, there are many well-characterized, as well as some newly ...
April Lowell, PhD Apr 7, 2021

The Role of Metabolism in Cancer

Alterations in the cellular metabolism of malignant cells have long been a central focus of cancer r...
Chris Sumner Mar 24, 2021

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