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The official blog of Cell Signaling Technology, where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Hypoxia and Its Role in Metabolism

Hypoxia—the deficiency of oxygen in the cellular environment—causes cellular stress and alters norma...
Chris SumnerJun 8, 2022

Novel Therapeutic Approaches for Diffuse Large B-Cell Lymphoma

Lymphoma is a cancer of the lymphatic system, a principal part of the body’s immune system. Lymphoma...
Andrea Tu, PhDMay 11, 2022

Pancreatic Cancer: Targeting Novel Drivers in the Tumor Microenvironment

Pancreatic cancer is devastating and difficult to diagnose early. The organ is located deep inside t...
Andrea Tu, PhDApr 27, 2022

Which Fluorophores Can I Combine in My Flow Cytometry Experiment?

Flow cytometry offers the exciting ability to detect and quantify multiple readouts per cell, enabli...
Rob MacDonald, PhDApr 13, 2022

Strategies for Successful Multiplex IF Experiments Using Conjugated Antibodies

One of the benefits of working with immunofluorescent (IF) analysis is the ability to compare multip...
Ginny Bain, PhDApr 6, 2022

Melanoma: Aberrant Signaling Pathways and Therapeutic Approaches

There are three major types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melan...
Andrea Tu, PhDMar 30, 2022

Flow Cytometry Antibody Staining Guide: Surface vs. Intracellular Protocols Explained

Getting started with flow cytometry or beginning to branch out from working solely with live cells t...
Rob MacDonald, PhDMar 23, 2022

Antibodies for Identifying the Protein Modification O-GlcNAc

Rajan Burt, Samuel Myers, and colleagues from the La Jolla Institute for Immunology, Broad Institute...

Tools to Confirm Antibody Specificity

You want to generate accurate results. You’ve planned out your experiment, accounting for all necess...
Chris SumnerMar 2, 2022

Emerging Therapeutic Approaches for Prostate Cancer

Approximately one in eight men will be diagnosed with prostate cancer during their lifetime, making ...
Andrea Tu, PhDFeb 23, 2022

The Importance of the ISG15 Protein in COVID-19 Research

Historically, the ISG15 protein hasn’t been thoroughly investigated by researchers. We know it can f...

Rising Black Scientists of 2022

We’re excited to present the 2022 recipients of the Rising Black Scientist Awards. This is only the ...
Chris SumnerFeb 2, 2022

Tools for Classifying Cells and Identifying Protein Localization

When do I want to classify cells? Why do I care where a protein localizes? These are actually two di...
Andrea Tu, PhDJan 26, 2022

Subcellular Marker Selection for Immunofluorescence

When performing immunofluorescence (IF) experiments, researchers often multiplex with several antibo...
Ginny Bain, PhDJan 12, 2022

Multiplexing the Brain: A Galaxy of Possibilities

The average human brain contains over 100 billion cells, which is nearly the same number as there ar...
Richard Cho, PhDDec 15, 2021

Analyzing PTM Activation State Using Western Blotting

Post-translational modifications (PTMs) are a critical regulatory mechanism that allows cells to tig...
Andrea Tu, PhDDec 8, 2021

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