CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Immunology: Immunophenotyping Using Flow Cytometry or IHC

In the field of immunology and immuno-oncology, immunophenotyping is a technique that uses antibodie...
Chris Sumner Jun 30, 2021

Neuroinflammation in Neurodegenerative Diseases

Neuroinflammation is the activation of an immune response in the central nervous system (CNS; brain ...
Chris Sumner Jun 23, 2021

Autophagy: Taking Out the Cellular Trash Has Widespread Therapeutic Implications

The term “autophagy” introduced by the biochemist Christian de Duve in 1963 is derived from the Gree...
Gary Kasof, PhD Jun 16, 2021

Cancer Biomarker Antibody Selection for IHC

What are cancer biomarkers? Biomarkers are naturally occurring molecules that can be used as indicat...

What is glycolysis and what is its role in metabolism?

Glycolysis and oxidative respiration are the two major metabolic pathways cells employ in order to c...
Chris Sumner May 26, 2021

Neurotransmitters, Receptors, and Transporters

Neurons are central nervous system (CNS) cells that receive and transmit electrochemical signals by ...
Chris Sumner May 19, 2021

Unraveling the Role of G3BPs in the Regulation of Cellular Energetics

In an article published by Prentzell et al in Cell, scientists used around 30 different CST antibodi...

Mechanisms of Cell Death: Necrosis & Necroptosis

The thought of necrotic cell death might bring to mind images from an old horror movie, but as with ...
April Lowell, PhD Apr 28, 2021

Which assays can be used to measure metabolism?

Several different assays can be used to measure metabolism in a variety of contexts. These include m...
Chris Sumner Apr 21, 2021

Mechanisms of Cell Death: Pyroptosis

Under the category of necrotic cell death, there are many well-characterized, as well as some newly ...
April Lowell, PhD Apr 7, 2021

The Role of Metabolism in Cancer

Alterations in the cellular metabolism of malignant cells have long been a central focus of cancer r...
Chris Sumner Mar 24, 2021

Which Antibody-Based Techniques Can Be Used to Study Neurodegenerative Diseases?

In order to derive the most information from samples related to neurodegenerative disease, it is imp...
Chris Sumner Mar 17, 2021

Cellular Pathways to Metabolism

Cellular homeostasis is regulated by the coordinated activity of several key metabolic pathways. The...
Chris Sumner Mar 3, 2021

Introducing the First Rising Black Scientists Awards Recipients

We’re excited to present the first-ever Rising Black Scientists Awards recipients. This will be an a...
Chris Sumner Feb 24, 2021

Targeting TIGIT for Cancer Immunotherapy & T Cell Exhaustion

The evolution of solid tumor cancer treatment has historically centered on a tripartite approach tha...
Tamar Aprahamian, PhD Feb 17, 2021

Neurodegeneration: Tau Protein and Neurofibrillary Tangles

Tau is a microtubule-associated protein expressed predominantly in the parts of the brain that funct...
Chris Sumner Feb 10, 2021

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