CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Lab Expectations listing page

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Targeting TIGIT for Immunotherapy and T Cell Exhaustion

The evolution of solid tumor cancer treatment has historically centered on a tripartite approach tha...
Tamar Aprahamian, PhD Feb 17, 2021

Neurodegeneration: Tau Protein and Neurofibrillary Tangles

Tau is a microtubule-associated protein expressed predominantly in the parts of the brain that funct...
Chris Sumner Feb 10, 2021

Introduction to Metabolism

Cellular metabolism encompasses all of the chemical processes that occur within cells to maintain ho...
Chris Sumner Feb 3, 2021

How S6 Ribosomal Protein (5G10) Rabbit mAb Can Help You With Your Immunofluorescence Staining

One antibody is used in our lab so often that we each keep our own bulk stock! This antibody is S6 R...
John B Jan 27, 2021

What Is Neurodegenerative Disease?

Neurodegeneration is marked by the progressive loss of neuronal function and structure leading to co...
Chris Sumner Jan 20, 2021

Chasing Tau-biomarkers for Alzheimer’s Disease [Part 2]

This is Part 2 of a two-part blog series on Alzheimer's Disease. Read Part 1 here. What plasma bioma...
Antonio V and Lei L Jan 13, 2021

2021 Preview

It’s the start of another exciting year of Lab Expectation articles. What can you expect from us in ...
Chris Sumner Jan 6, 2021

Case Study: Acetylated Lysine and Its Impact on Crohn’s Disease

Nature Communications recently published a novel study from the laboratory of Daniel Figeys at the U...

A Tale of Two Stains: Ponceau S vs Coomassie Blue

You've just finished running your lysate sample by SDS-PAGE, so you're pretty confident your protein...

Chasing Tau-biomarkers for Alzheimer’s Disease [Part 1]

Dementia is an inevitable burden for many, prevailing under a broad umbrella not only in neurologica...
Antonio V and Lei L Dec 2, 2020

B Cell Basics: What a Disease Researcher Needs to Know

Changes in the activation of intracellular signaling networks downstream of B-cell receptors (BCR) l...
Tamar Aprahamian, PhD Nov 18, 2020

T Cell Basics: What a Disease Researcher Needs to Know

T cells are highly specialized lymphocytes that play a critical role in the cell-mediated arm of the...
Tamar Aprahamian, PhD Nov 11, 2020

COVID-19 and Fibrosis: Long-term Damage Beyond Acute Respiratory Symptoms

At the time of writing, the SARS-CoV-2 virus, responsible for COVID-19, has infected more than 28 mi...
Antony Wood, PhD Nov 4, 2020

The Role of Autophagy and ER Stress in Viral Infection

The regulation of ER stress and autophagy during viral infection is an important factor in the balan...
Gary Kasof, PhD Oct 28, 2020

The Role of Cell Death in Viral Infection

The regulation of cell death during viral infection is an important factor in the balance of virus a...
Gary Kasof, PhD Oct 21, 2020

Cell Process: Which markers can be used to identify cellular senescence?

In response to a variety of environmental factors—like ionizing radiation, exposure to chemotherapeu...
Tamar Aprahamian, PhD Oct 14, 2020

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