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The official blog of Cell Signaling Technology, where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Which Antibody-Based Techniques Can Be Used to Study Neurodegenerative Diseases?

In order to derive the most information from samples related to neurodegenerative disease, it is imp...
Chris Sumner Mar 17, 2021

Cellular Pathways to Metabolism

Cellular homeostasis is regulated by the coordinated activity of several key metabolic pathways. The...
Chris Sumner Mar 3, 2021

Introducing the First Rising Black Scientists Awards Recipients

We’re excited to present the first-ever Rising Black Scientists Awards recipients. This will be an a...
Chris Sumner Feb 24, 2021

Targeting TIGIT for Cancer Immunotherapy & T Cell Exhaustion

The evolution of solid tumor cancer treatment has historically centered on a tripartite approach tha...
Tamar Aprahamian, PhD Feb 17, 2021

Neurodegeneration: Tau Protein and Neurofibrillary Tangles

Tau is a microtubule-associated protein expressed predominantly in the parts of the brain that funct...
Chris Sumner Feb 10, 2021

How S6 Ribosomal Protein (5G10) Rabbit Antibody Can Help You With Your IF Staining

One antibody is used in our lab so often that we each keep our own bulk stock! This antibody is S6 R...

What is Neurodegeneration?

Neurodegeneration is marked by the progressive loss of neuronal function and structure, leading to c...
Chris Sumner Jan 20, 2021

Chasing Tau-biomarkers for Alzheimer’s Disease: Part 2

This is Part 2 of a two-part blog series on Alzheimer's Disease. Read Part 1 here. Finding a Diagnos...
Antonio V and Lei L Jan 13, 2021

Case Study: Acetylated Lysine and Its Impact on Crohn’s Disease

Nature Communications recently published a novel study from the laboratory of Daniel Figeys at the U...

A Tale of Two Stains: Ponceau S vs Coomassie Blue

You've just finished running your lysate sample by SDS-PAGE, so you're pretty confident your protein...

Chasing Tau-biomarkers for Alzheimer’s Disease: Part 1

Dementia is an inevitable burden for many, prevailing under a broad umbrella not only in neurologica...
Antonio V and Lei L Dec 2, 2020

B Cell Basics: Markers, Signaling Pathways & Immune Outcomes

Changes in the activation of intracellular signaling networks downstream of B-cell receptors (BCR) l...
Tamar Aprahamian, PhD Nov 18, 2020

T Cell Basics: What a Disease Researcher Needs to Know

T cells are highly specialized lymphocytes that play a critical role in the cell-mediated arm of the...
Tamar Aprahamian, PhD Nov 11, 2020

COVID-19 and Fibrosis: Long-term Damage Beyond Acute Respiratory Symptoms

At the time of writing, the SARS-CoV-2 virus, responsible for COVID-19, has infected more than 28 mi...
Antony Wood, PhD Nov 4, 2020

The Role of Autophagy and ER Stress in Viral Infection

The regulation of ER stress and autophagy during viral infection is an important factor in the balan...
Gary Kasof, PhD Oct 28, 2020

The Role of Cell Death in Viral Infection

The regulation of cell death during viral infection is an important factor in the balance of virus a...
Gary Kasof, PhD Oct 21, 2020

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