CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Chasing Tau-biomarkers for Alzheimer’s Disease [Part 2]

This is Part 2 of a two-part blog series on Alzheimer's Disease. Read Part 1 here. What plasma bioma...
Antonio V and Lei L Jan 13, 2021

Case Study: Acetylated Lysine and Its Impact on Crohn’s Disease

Nature Communications recently published a novel study from the laboratory of Daniel Figeys at the U...

A Tale of Two Stains: Ponceau S vs Coomassie Blue

You've just finished running your lysate sample by SDS-PAGE, so you're pretty confident your protein...

Chasing Tau-biomarkers for Alzheimer’s Disease [Part 1]

Dementia is an inevitable burden for many, prevailing under a broad umbrella not only in neurologica...
Antonio V and Lei L Dec 2, 2020

B Cell Basics: What a Disease Researcher Needs to Know

Changes in the activation of intracellular signaling networks downstream of B-cell receptors (BCR) l...
Tamar Aprahamian, PhD Nov 18, 2020

T Cell Basics: What a Disease Researcher Needs to Know

T cells are highly specialized lymphocytes that play a critical role in the cell-mediated arm of the...
Tamar Aprahamian, PhD Nov 11, 2020

COVID-19 and Fibrosis: Long-term Damage Beyond Acute Respiratory Symptoms

At the time of writing, the SARS-CoV-2 virus, responsible for COVID-19, has infected more than 28 mi...
Antony Wood, PhD Nov 4, 2020

The Role of Autophagy and ER Stress in Viral Infection

The regulation of ER stress and autophagy during viral infection is an important factor in the balan...
Gary Kasof, PhD Oct 28, 2020

The Role of Cell Death in Viral Infection

The regulation of cell death during viral infection is an important factor in the balance of virus a...
Gary Kasof, PhD Oct 21, 2020

Cell Process: Which markers can be used to identify cellular senescence?

In response to a variety of environmental factors—like ionizing radiation, exposure to chemotherapeu...
Tamar Aprahamian, PhD Oct 14, 2020

Cell Process: What role does senescence play in disease?

Cellular senescence occurs when cells cease proliferation and irreversibly exit the cell cycle. Whil...
Tamar Aprahamian, PhD Oct 7, 2020

Simplify iPSCs Research: Antibodies to Identify Pluripotency Markers

Reagent validation and experiment reproducibility are critical for advancing research in any scienti...
Chris Sumner Sep 30, 2020

Seeding Labs Gives Old Lab Equipment a Second Life

As stewards of the planet, we’re always trying to find ways to reduce our corporate carbon footprint...
Chris Sumner Sep 23, 2020

Cell Process: What role do the telomeres play in senescence?

Senescence is a cellular state during which cells remain metabolically active, but irreversibly with...
Tamar Aprahamian, PhD Sep 16, 2020

Cell Process: How is cellular senescence related to aging?

Senescence, the cessation of cell division and permanent withdrawal from the cell cycle, is a proces...
Tamar Aprahamian, PhD Sep 9, 2020

Recommended Best Practices for Lysate Handling

The preparation of a cell lysate is crucial to the success of many assays, including techniques that...
Michelle Graham Sep 2, 2020

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