CST BLOG

The official blog of Cell Signaling Technology, where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Tools for Classifying Cells and Identifying Protein Localization

When do I want to classify cells? Why do I care where a protein localizes? These are actually two di...
Andrea Tu, PhD Jan 26, 2022

Subcellular Marker Selection for Immunofluorescence

When performing immunofluorescence (IF) experiments, researchers often multiplex with several antibo...
Ginny Bain, PhD Jan 12, 2022

Multiplexing the Brain: A Galaxy of Possibilities

The average human brain contains over 100 billion cells, which is nearly the same number as there ar...
Richard Cho, PhD Dec 15, 2021

Analyzing PTM Activation State Using Western Blotting

Post-translational modifications (PTMs) are a critical regulatory mechanism that allows cells to tig...
Andrea Tu, PhD Dec 8, 2021

Tools to Perform Genomic Profiling

Techniques used in genomic profiling have come a long way in the past few decades. Researchers can n...
Curtis Desilets Dec 1, 2021

Why use viability dyes in flow cytometry experiments?

Viability dyes are widely used when counting and passaging cells, assessing chemical toxicity, and p...
Rob MacDonald, PhD Nov 17, 2021

Emerging Discoveries in ER-Phagy

Autophagy is a catabolic process for the disposal of cytoplasmic contents that are captured by doubl...
Gary Kasof, PhD Nov 3, 2021

The Role of Metabolism in Disease

Metabolism plays a central role in many diseases, including diabetes, cardiovascular disease, obesit...
Chris Sumner Oct 27, 2021

Tools for Screening & Quantifying Proteins: ELISA vs Mass Spectrometry

Whether your heart is devoted to cardiac research, you’re excited to investigate neurodegenerative d...

Tools for Modulating Cells

Cell behavior is a tightly regulated, finely tuned process where various different signals work toge...
Andrea Tu, PhD Oct 13, 2021

Assay Kits and Tools for Monitoring Cell State

Have you been wondering how to monitor a cell state or cellular response? From a basic research stan...
Andrea Tu, PhD Oct 6, 2021

The Importance of Using a Validated Antibody Pair in a High-throughput Immunoassay

Over the years, there have been numerous additions and variations to the original ELISA format, incl...

Xenophagy: What You Eat Can’t Hurt You

Xenophagy provides an important defense against foreign pathogens such as bacteria and viruses by ta...
Gary Kasof, PhD Sep 15, 2021

Writing a Research Grant: What Are My Chances of Acceptance?

The late nights, the writer’s block, the last harried review of all of the components is finished. T...
Tamar Aprahamian, PhD Sep 8, 2021

Writing a Research Grant: Interpreting Summary Statement & Reviewer’s Critiques

You received your National Institutes of Health (NIH) scoring notice and hopefully 1) your grant got...
Tamar Aprahamian, PhD Sep 1, 2021

Writing A Research Grant: Budget Justification, Support Letters, & More

Previous posts in the grant writing series have dealt with many of the different parts of the grant ...
Tamar Aprahamian, PhD Aug 25, 2021

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