CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Lab Expectations listing page

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SignalStar™ Multiplex IHC: Speed Your Spatial Biology Research with Ready-to-Use, 8-Plex Antibody Panels

Enabled by recent advances in sequencing, mass spectrometry, and fluorescence microscopy, spatial bi...
Sarah Klein, PhD Sep 12, 2023

IHC-Validated p16 INK4A Antibody: Jump-Start Your Senescence Research

Cell cycle regulation is vital to maintain tissue homeostasis and to prevent sustained proliferative...
Alexandra Foley Apr 19, 2023

World Cancer Day: A Global Call to Action

What is World Cancer Day? Most people will either be directly or indirectly affected by a cancer dia...
Alexandra Foley Feb 6, 2023

Immunology: Immunophenotyping Basics

Immunophenotyping is a technique that uses antibodies to allow the identification and quantification...
Chris Sumner Jun 30, 2021

Streamline Cancer Biomarker Antibody Selection for IHC with this eBook

Biomarkers are naturally occurring molecules that can be used as indicators of a normal biological p...
Emma E Jun 9, 2021

Targeting TIGIT for Immunotherapy and T Cell Exhaustion

The evolution of solid tumor cancer treatment has historically centered on a tripartite approach tha...
Tamar A Feb 17, 2021

Simplify the Identification of Pluripotent Stem Cells

Reagent validation and experiment reproducibility are critical for advancing research of any scienti...
Harald M and Chris S Sep 30, 2020

Pros and Cons of Different Multiplexing Techniques for IHC and IF

Multiplex immunohistochemistry (mIHC) and multiplex immunofluorescence (mIF) are widely used to iden...
Alexandra Foley Jul 22, 2020

10 Must-have Markers for Senescence Research

Understanding when and why cell cycle arrest occurs is critical to many fields of research, includin...
Tamar A May 13, 2020

Dual Staining Mouse CD8 and FoxP3 with Confidence

For decades, immunohistochemistry (IHC) has been a powerful technique for the investigation and visu...
Tamar A Sep 25, 2019

Visualize and Understand Protein Co-expression during EMT

Careful planning and the fine tuning of experimental protocols are key to ensuring clear, interpreta...
Tamar A Aug 7, 2019

Video: Can you trust your immunohistochemistry results?

Immunohistochemistry, or IHC, remains the simplest method for detecting biomarker expression while m...
Chris Sumner Jun 19, 2019

If I Could Only See What’s Going on Inside Your Brain...

For generations of neuroscientists, using immunohistochemistry to study the brain in its anatomical ...
Richard Cho, PhD Jun 5, 2019

Demystifying Antibody Panel Design for Multiplex IHC

In recent years, immune checkpoint proteins in the tumor microenvironment have been under intense st...
Jen Z Oct 10, 2018

Characterize Myeloid Cell Mediated Immunosuppression in the Tumor Microenvironment Using Multiplex IHC

The clinical validation of immune checkpoint inhibitors as immunotherapeutic agents for a variety of...
Neha G Jan 24, 2018

Switching from Manual to Automated IHC? We've got your back

If you’ve ever transitioned your IHC experiments from a manual protocol to an automated platform, yo...
Chris G Aug 30, 2017

4 Steps to Better Immunohistochemistry: Steps 2, 3, and 4

This is part two of a two-part series on how to optimize your IHC protocols. Part one introduced the...
Carolyn P May 31, 2017

Four Steps to Better Immunohistochemistry: Step 1 - Antigen Retrieval

It’s Friday night and you could be out with your friends right now, but instead you’re tucked away i...
Carolyn P May 24, 2017

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