CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology® (CST) where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Tools for Classifying Cells and Identifying Protein Localization

When do I want to classify cells? Why do I care where a protein localizes? These are actually two di...
Andrea T Jan 26, 2022

Immunology: Which Cells Have a Lymphoid Lineage and How Are They Identified?

In humans, hematopoietic stem cells (HSCs) continuously replenish all types of blood cells via a ser...
Emma E Jan 19, 2022

Tools for Monitoring Cell State

Have you been wondering how to monitor a cell state or cellular response? From a basic research stan...
Andrea T Oct 6, 2021

Streamline Cancer Biomarker Antibody Selection for IHC with this eBook

Biomarkers are naturally occurring molecules that can be used as indicators of a normal biological p...
Emma E Jun 9, 2021

Pros and Cons of Different Multiplexing Techniques: mIHC and mIF

Multiplex immunohistochemistry (mIHC) and multiplex immunofluorescence (mIF) are widely used to iden...
Emma E Jul 22, 2020

10 Must-have Markers for Senescence Research

Understanding when and why cell cycle arrest occurs is critical to many fields of research, includin...
Tamar A May 13, 2020

Critical Considerations for Optimizing Imaging Mass Cytometry

Understanding the microenvironment of disease is critical for the success of targeted therapies. For...
Chris S Nov 20, 2019

IMC: Endless Possibilities to Understand the Microenvironment of Disease

Understanding the microenvironment of disease is critical. Targeted cancer therapies may not be effe...
Kris H Oct 23, 2019

Dual Staining Mouse CD8 and FoxP3 with Confidence

For decades, immunohistochemistry (IHC) has been a powerful technique for the investigation and visu...
Tamar A Sep 25, 2019

Visualize and Understand Protein Co-expression during EMT

Careful planning and the fine tuning of experimental protocols are key to ensuring clear, interpreta...
Tamar A Aug 7, 2019

Video: Can you trust your immunohistochemistry results?

Immunohistochemistry, or IHC, remains the simplest method for detecting biomarker expression while m...
Chris S Jun 19, 2019

If I could only see what’s going on inside your brain...

For generations of neuroscientists, using immunohistochemistry to study the brain in its anatomical ...
Richard C Jun 5, 2019

Demystifying Antibody Panel Design for Multiplex IHC

In recent years, immune checkpoint proteins in the tumor microenvironment have been under intense st...
Jen Z Oct 10, 2018

GPNMB: A Promising Immunotherapeutic Target for Triple Negative Breast Cancer

The last few years have witnessed several breakthroughs in the immuno-oncology space. Treatments tha...
Amrik Singh, PhD Apr 4, 2018

Switching from Manual to Automated IHC? We've got your back

If you’ve ever transitioned your IHC experiments from a manual protocol to an automated platform, yo...
Chris G Aug 30, 2017

Webinar | Highly Multiplexed Single Cell Analysis of Tumor Heterogeneity through Time and Space by Mass Cytometry

The study of the tumor ecosystem and its cell-to-cell communications is essential to enable an under...
Chris S Jun 21, 2017

4 Steps to Better Immunohistochemistry: Steps 2, 3, and 4

This is part two of a two-part series on how to optimize your IHC protocols. Part one introduced the...
Carolyn P May 31, 2017

4 Steps to Better Immunohistochemistry: Step 1 - Antigen Retrieval

It’s Friday night and you could be out with your friends right now, but instead you’re tucked away i...
Carolyn P May 24, 2017

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