CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology® (CST) where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Lab Expectations listing page

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World Cancer Day: A Global Call to Action

What is World Cancer Day? Most people will either be directly or indirectly affected by a cancer dia...
Alexandra Foley Feb 6, 2023

Tools for Classifying Cells and Identifying Protein Localization

When do I want to classify cells? Why do I care where a protein localizes? These are actually two di...
Andrea T Jan 26, 2022

Immunology: Which Cells Have a Lymphoid Lineage and How Are They Identified?

In humans, hematopoietic stem cells (HSCs) continuously replenish all types of blood cells via a ser...
Emma E Jan 19, 2022

Tools for Monitoring Cell State

Have you been wondering how to monitor a cell state or cellular response? From a basic research stan...
Andrea T Oct 6, 2021

Streamline Cancer Biomarker Antibody Selection for IHC with this eBook

Biomarkers are naturally occurring molecules that can be used as indicators of a normal biological p...
Emma E Jun 9, 2021

Pros and Cons of Different Multiplexing Techniques for mIHC and mIF

Multiplex immunohistochemistry (mIHC) and multiplex immunofluorescence (mIF) are widely used to iden...
Emma E Jul 22, 2020

10 Must-have Markers for Senescence Research

Understanding when and why cell cycle arrest occurs is critical to many fields of research, includin...
Tamar A May 13, 2020

Hallmarks of Antibody Validation: Heterologous Strategy

For antigenic targets where expression of the protein is very low or unknown, the use of recombinant...
Katie Crosby Apr 1, 2020

Critical Considerations for Optimizing Imaging Mass Cytometry

Understanding the microenvironment of disease is critical for the success of targeted therapies. For...
Chris Sumner Nov 20, 2019

Dual Staining Mouse CD8 and FoxP3 with Confidence

For decades, immunohistochemistry (IHC) has been a powerful technique for the investigation and visu...
Tamar A Sep 25, 2019

Visualize and Understand Protein Co-expression during EMT

Careful planning and the fine tuning of experimental protocols are key to ensuring clear, interpreta...
Tamar A Aug 7, 2019

Video: Can you trust your immunohistochemistry results?

Immunohistochemistry, or IHC, remains the simplest method for detecting biomarker expression while m...
Chris Sumner Jun 19, 2019

If I Could Only See What’s Going on Inside Your Brain...

For generations of neuroscientists, using immunohistochemistry to study the brain in its anatomical ...
Richard Cho, PhD Jun 5, 2019

Demystifying Antibody Panel Design for Multiplex IHC

In recent years, immune checkpoint proteins in the tumor microenvironment have been under intense st...
Jen Z Oct 10, 2018

GPNMB: A Promising Immunotherapeutic Target for Triple Negative Breast Cancer

The last few years have witnessed several breakthroughs in the immuno-oncology space. Treatments tha...
Amrik Singh, PhD Apr 4, 2018

Switching from Manual to Automated IHC? We've got your back

If you’ve ever transitioned your IHC experiments from a manual protocol to an automated platform, yo...
Chris G Aug 30, 2017

Webinar | Highly Multiplexed Single Cell Analysis of Tumor Heterogeneity through Time and Space by Mass Cytometry

The study of the tumor ecosystem and its cell-to-cell communications is essential to enable an under...
Chris Sumner Jun 21, 2017

4 Steps to Better Immunohistochemistry: Steps 2, 3, and 4

This is part two of a two-part series on how to optimize your IHC protocols. Part one introduced the...
Carolyn P May 31, 2017

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