CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Lab Expectations listing page

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Mechanisms of Cell Death: Pyroptosis

Under the category of necrotic cell death, there are many well-characterized, as well as some newly ...
April Lowell, PhD Apr 7, 2021

The Role of Metabolism in Cancer

Alterations in the cellular metabolism of malignant cells have long been a central focus of cancer r...
Chris Sumner Mar 24, 2021

Which Antibody-Based Techniques Can Be Used to Study Neurodegenerative Diseases?

In order to derive the most information from samples related to neurodegenerative disease, it is imp...
Chris Sumner Mar 17, 2021

Mechanisms of Cell Death: Apoptosis

The death of a cell may be a more complex process than one might initially imagine. Cells expire in ...
April Lowell, PhD Mar 10, 2021

Cellular Pathways to Metabolism

Cellular homeostasis is regulated by the coordinated activity of several key metabolic pathways. The...
Chris Sumner Mar 3, 2021

Introducing the First Rising Black Scientists Awards Recipients

We’re excited to present the first-ever Rising Black Scientists Awards recipients. This will be an a...
Chris Sumner Feb 24, 2021

Targeting TIGIT for Immunotherapy and T Cell Exhaustion

The evolution of solid tumor cancer treatment has historically centered on a tripartite approach tha...
Tamar A Feb 17, 2021

Neurodegeneration: Tau Protein and Neurofibrillary Tangles

Tau is a microtubule-associated protein expressed predominantly in the parts of the brain that funct...
Chris Sumner Feb 10, 2021

Introduction to Metabolism

Cellular metabolism encompasses all of the chemical processes that occur within cells to maintain ho...
Chris Sumner Feb 3, 2021

How S6 Ribosomal Protein (5G10) Rabbit mAb Can Help You With Your Immunofluorescence Staining

One antibody is used in our lab so often that we each keep our own bulk stock! This antibody is S6 R...
John B Jan 27, 2021

What Is Neurodegenerative Disease?

Neurodegeneration is marked by the progressive loss of neuronal function and structure leading to co...
Chris Sumner Jan 20, 2021

Chasing Tau-biomarkers for Alzheimer’s Disease [Part 2]

This is Part 2 of a two-part blog series on Alzheimer's Disease. Read Part 1 here. What plasma bioma...
Antonio V and Lei L Jan 13, 2021

2021 Preview

It’s the start of another exciting year of Lab Expectation articles. What can you expect from us in ...
Chris Sumner Jan 6, 2021

Case Study: Acetylated Lysine and Its Impact on Crohn’s Disease

Nature Communications recently published a novel study from the laboratory of Daniel Figeys at the U...
Charles F and Josh N Dec 16, 2020

A Tale of Two Stains: Ponceau S vs Coomassie Blue

You've just finished running your lysate sample by SDS-PAGE, so you're pretty confident your protein...

Chasing Tau-biomarkers for Alzheimer’s Disease [Part 1]

Dementia is an inevitable burden for many, prevailing under a broad umbrella not only in neurologica...
Antonio V and Lei L Dec 2, 2020

B Cell Basics: What a Disease Researcher Needs to Know

Changes in the activation of intracellular signaling networks downstream of B-cell receptors (BCR) l...
Tamar A Nov 18, 2020

T Cell Basics: What a Disease Researcher Needs to Know

T cells are highly specialized lymphocytes that play a critical role in the cell-mediated arm of the...
Tamar A Nov 11, 2020

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