CST BLOG

The official blog of Cell Signaling Technology, where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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PI3K/Akt Signaling Targets Hit Close to Home

The ability of cells to recognize external signal cues (ligands and nutrients) and appropriately res...

How can recombinant proteins help researchers study SARS-CoV-2?

Although coronaviruses have long circulated throughout human populations, the study of these viruses...
Tamar Aprahamian, PhD Aug 5, 2020

Immunology: How does the adaptive immune system work?

Have you ever wondered how people are able to develop immunity to specific diseases? This important ...
April Lowell, PhD Jul 29, 2020

Pros and Cons of Different Multiplexing Techniques for IHC and IF

Multiplex immunohistochemistry (mIHC) and multiplex immunofluorescence (mIF) are widely used to iden...

What is a Recombinant Antibody and Why is it Important?

Recombinant antibodies offer several key advantages compared to traditional antibodies. These includ...

Cell Process: How is cytotoxicity assessed?

Changes in cellular health in response to exogenous stimuli can provide keen insight into the biolog...
Tamar Aprahamian, PhD Jul 8, 2020

Seven Assays to Detect Apoptosis

Apoptosis is a highly regulated form of programmed cell death that occurs in multicellular organisms...
Tamar Aprahamian, PhD Jul 1, 2020

Control Your Western Blot: Loading Control Expression in Mouse Tissues

When it comes to mouse tissue samples, not all western blot (WB) loading control proteins are expres...
Supriya Singh, PhD Jun 24, 2020

Immunology: What are toll-like receptors and how do they invoke tumor tolerance?

Toll-like receptors (TLRs) are transmembrane receptors that play a critical role in innate immune re...
Tamar Aprahamian, PhD Jun 10, 2020

Antibody Selection for Epitope Tagging: Insights from Myc-Tag Performance

Biological research is about expanding knowledge, so it's not uncommon for scientists to study prote...
Tamar Aprahamian, PhD May 20, 2020

10 Must-Have Markers for Senescence Research

Understanding when and why cell cycle arrest occurs is critical to many fields of research, includin...
Tamar Aprahamian, PhD May 13, 2020

Cell Process - How is cell proliferation quantified?

The production of new cells through cellular proliferation impacts the development, growth, and main...
Tamar Aprahamian, PhD Apr 22, 2020

Cell Process: What is cell viability and how can it be measured?

The health of cells in culture is critical to the success of your experiments. Have you ever been ex...
Tamar Aprahamian, PhD Apr 15, 2020

Hallmarks of Validation - Complementary Strategies

Depending on the antigenic target being studied and the application being used, it may be advisable ...
Katie Crosby Apr 8, 2020

Hallmarks of Antibody Validation: Heterologous Strategy

For antigenic targets where expression of the protein is very low or unknown, the use of recombinant...
Katie Crosby Apr 1, 2020

Fibrosis: When Wound Healing Turns to Disease

Fibrosis is a disease that is characterized by scarring and hardening of tissues and organs. Fibrosi...
Susan Keezer, PhD Mar 25, 2020

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