CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Cell Process: What is cell viability and how can it be measured?

The health of cells in culture is critical to the success of your experiments. Have you ever been ex...
Tamar Aprahamian, PhD Apr 15, 2020

Hallmarks of Validation - Complementary Strategies

Depending on the antigenic target being studied and the application being used, it may be advisable ...
Katie Crosby Apr 8, 2020

Hallmarks of Antibody Validation: Heterologous Strategy

For antigenic targets where expression of the protein is very low or unknown, the use of recombinant...
Katie Crosby Apr 1, 2020

Fibrosis: When Wound Healing Turns to Disease

Fibrosis is a disease that is characterized by scarring and hardening of tissues and organs. Fibrosi...
Susan Keezer, PhD Mar 25, 2020

Hallmarks of Validation - Multiple Antibody Strategy

A multiple antibody strategy is a powerful approach to antibody validation. One of the most common m...
Katie Crosby Mar 18, 2020

CiteAb Awards: Antibody Supplier of the Decade & Antibody Supplier Succeeding in Alzheimer's Research

We’re honored to win two CiteAb awards in 2020: Antibody Supplier of the Decade and Antibody Supplie...
Chris Sumner Mar 11, 2020

Hallmarks of Validation - Ranged Strategy

While a binary approach is one of the more desirable ways to evaluate antibody specificity, binary m...
Katie Crosby Feb 19, 2020

Immunology: How does the innate immune system work?

As we touched on in a previous blog post, the innate immune system is an important part of our body'...
April Lowell, PhD Feb 12, 2020

Hallmarks of Antibody Validation - Binary Strategy

A binary approach is one of the best ways to evaluate antibody specificity. By testing an antibody i...
Katie Crosby Jan 22, 2020

Immunology: How does our immune system protect us?

Scientists and medical professionals have been studying what makes us sick and the myriad mechanisms...
April Lowell, PhD Jan 8, 2020

Tissue Clearing from a Microscope Enthusiast’s Perspective

Biological imaging data has massive potential in terms of complexity of experiment and richness of d...
Ginny Bain, PhD Oct 30, 2019

IMC: Endless Possibilities to Understand the Microenvironment of Disease

Understanding the microenvironment of disease is critical. Targeted cancer therapies may not be effe...

The Researcher's Guide to the Hallmarks of Cancer Research Targets

If you haven’t heard already, it’s CST’s 20th anniversary. Woohoo! You could say this year is kind o...
Chris Sumner Oct 9, 2019

Dual Staining Mouse CD8 and FoxP3 with Confidence

For decades, immunohistochemistry (IHC) has been a powerful technique for the investigation and visu...
Tamar Aprahamian, PhD Sep 25, 2019

How to Prepare a ChIP-seq DNA Library

Chromatin immunoprecipitation sequencing (ChIP-seq) is a flexible and powerful technique used by res...
Tamar Aprahamian, PhD Sep 18, 2019

Hallmarks of Cancer: Genome Instability and Mutation

Not all cancer cells are equal, they evolve in response to selective pressure driven by accumulation...
Chris Sumner Aug 28, 2019

    Recent Posts