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The official blog of Cell Signaling Technology, where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Cell Process: What role do the telomeres play in senescence?

Senescence is a cellular state during which cells remain metabolically active, but irreversibly with...
Tamar Aprahamian, PhDSep 16, 2020

Cell Process: How is cellular senescence related to aging?

Senescence, the cessation of cell division and permanent withdrawal from the cell cycle, is a proces...

Western Blotting: Best Practices for Cell Lysate Preparation

The preparation of a cell lysate is crucial to the success of many assays, including techniques that...
Michelle GrahamSep 2, 2020

Which signaling pathways are associated with cellular senescence?

Senescence is the irreversible arrest of proliferation in response to a variety of cellular stressor...
Tamar Aprahamian, PhDAug 26, 2020

PI3K/Akt Signaling Targets Hit Close to Home

The ability of cells to recognize external signal cues (ligands and nutrients) and appropriately res...

How can recombinant proteins help researchers study SARS-CoV-2?

Although coronaviruses have long circulated throughout human populations, the study of these viruses...

Immunology: How does the adaptive immune system work?

Have you ever wondered how people are able to develop immunity to specific diseases? This important ...
April Lowell, PhDJul 29, 2020

Cell Process: How is cytotoxicity assessed?

Changes in cellular health in response to exogenous stimuli can provide keen insight into the biolog...

Seven Assays to Detect Apoptosis

Apoptosis is a highly regulated form of programmed cell death that occurs in multicellular organisms...

Control Your Western Blot: Loading Control Expression in Mouse Tissues

When it comes to mouse tissue samples, not all western blot (WB) loading control proteins are expres...
Supriya Singh, PhDJun 24, 2020

Immunology: What are toll-like receptors and how do they invoke tumor tolerance?

Toll-like receptors (TLRs) are transmembrane receptors that play a critical role in innate immune re...
Tamar Aprahamian, PhDJun 10, 2020

Antibody Selection for Epitope Tagging: Insights from Myc-Tag Performance

Biological research is about expanding knowledge, so it's not uncommon for scientists to study prote...
Tamar Aprahamian, PhDMay 20, 2020

10 Must-Have Markers for Senescence Research

Understanding when and why cell cycle arrest occurs is critical to many fields of research, includin...
Tamar Aprahamian, PhDMay 13, 2020

How is cell proliferation quantified?

The production of new cells through cellular proliferation impacts the development, growth, and main...
Tamar Aprahamian, PhDApr 22, 2020

What is cell viability and how can it be measured?

The health of cells in culture is critical to the success of your experiments. Have you ever been ex...
Tamar Aprahamian, PhDApr 15, 2020

Hallmarks of Validation - Complementary Strategies

Depending on the antigenic target being studied and the application being used, it may be advisable ...
Katie CrosbyApr 8, 2020

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