CST BLOG

The official blog of Cell Signaling Technology, where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Which markers can be used to identify cellular senescence?

In response to a variety of environmental factors—like ionizing radiation, exposure to chemotherapeu...
Tamar Aprahamian, PhD Oct 14, 2020

Cell Process: What role does senescence play in disease?

Cellular senescence occurs when cells cease proliferation and irreversibly exit the cell cycle. Whil...
Tamar Aprahamian, PhD Oct 7, 2020

Simplify iPSCs Research: Antibodies to Identify Pluripotency Markers

Reagent validation and experiment reproducibility are critical for advancing research in any scienti...
Chris Sumner Sep 30, 2020

Cell Process: What role do the telomeres play in senescence?

Senescence is a cellular state during which cells remain metabolically active, but irreversibly with...
Tamar Aprahamian, PhD Sep 16, 2020

Cell Process: How is cellular senescence related to aging?

Senescence, the cessation of cell division and permanent withdrawal from the cell cycle, is a proces...
Tamar Aprahamian, PhD Sep 9, 2020

Western Blotting: Best Practices for Cell Lysate Preparation

The preparation of a cell lysate is crucial to the success of many assays, including techniques that...
Michelle Graham Sep 2, 2020

Cell Process: Which signaling pathways are associated with cellular senescence?

Senescence is the irreversible arrest of proliferation in response to a variety of cellular stressor...
Tamar Aprahamian, PhD Aug 26, 2020

PI3K/Akt Signaling Targets Hit Close to Home

The ability of cells to recognize external signal cues (ligands and nutrients) and appropriately res...

How can recombinant proteins help researchers study SARS-CoV-2?

Although coronaviruses have long circulated throughout human populations, the study of these viruses...
Tamar Aprahamian, PhD Aug 5, 2020

Immunology: How does the adaptive immune system work?

Have you ever wondered how people are able to develop immunity to specific diseases? This important ...
April Lowell, PhD Jul 29, 2020

Pros and Cons of Different Multiplexing Techniques for IHC and IF

Multiplex immunohistochemistry (mIHC) and multiplex immunofluorescence (mIF) are widely used to iden...

What is a Recombinant Antibody and Why is it Important?

Recombinant antibodies offer several key advantages compared to traditional antibodies. These includ...

Cell Process: How is cytotoxicity assessed?

Changes in cellular health in response to exogenous stimuli can provide keen insight into the biolog...
Tamar Aprahamian, PhD Jul 8, 2020

Seven Assays to Detect Apoptosis

Apoptosis is a highly regulated form of programmed cell death that occurs in multicellular organisms...
Tamar Aprahamian, PhD Jul 1, 2020

Control Your Western Blot: Loading Control Expression in Mouse Tissues

When it comes to mouse tissue samples, not all western blot (WB) loading control proteins are expres...
Supriya Singh, PhD Jun 24, 2020

Immunology: What are toll-like receptors and how do they invoke tumor tolerance?

Toll-like receptors (TLRs) are transmembrane receptors that play a critical role in innate immune re...
Tamar Aprahamian, PhD Jun 10, 2020

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