CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Western Blotting: Best Practices for Cell Lysate Preparation

The preparation of a cell lysate is crucial to the success of many assays, including techniques that...
Michelle Graham Sep 2, 2020

Cell Process: Which signaling pathways are associated with cellular senescence?

Senescence is the irreversible arrest of proliferation in response to a variety of cellular stressor...
Tamar Aprahamian, PhD Aug 26, 2020

PI3K/Akt Signaling Targets Hit Close to Home

The ability of cells to recognize external signal cues (ligands and nutrients) and appropriately res...

How can recombinant proteins help researchers study SARS-CoV-2?

Although coronaviruses have long circulated throughout human populations, the study of these viruses...
Tamar Aprahamian, PhD Aug 5, 2020

Immunology: How does the adaptive immune system work?

Have you ever wondered how people are able to develop immunity to specific diseases? This important ...
April Lowell, PhD Jul 29, 2020

Pros and Cons of Different Multiplexing Techniques for IHC and IF

Multiplex immunohistochemistry (mIHC) and multiplex immunofluorescence (mIF) are widely used to iden...

What is a Recombinant Antibody and Why is it Important?

Recombinant antibodies offer several key advantages compared to traditional antibodies. These includ...

Cell Process: How is cytotoxicity assessed?

Changes in cellular health in response to exogenous stimuli can provide keen insight into the biolog...
Tamar Aprahamian, PhD Jul 8, 2020

Cell Process: Seven Assays to Detect Apoptosis

Apoptosis is a highly regulated form of programmed cell death that occurs in multicellular organisms...
Tamar Aprahamian, PhD Jul 1, 2020

Control Your Western Blot: Loading Control Expression in Mouse Tissues

When it comes to mouse tissue samples, not all western blot (WB) loading control proteins are expres...
Supriya Singh, PhD Jun 24, 2020

Protect Your Drug Development Pipeline: Don't Let Antibody Supply Disrupt Your Progress

For many researchers, choosing the right antibody for a project is one of the most important parts o...
Josh Nathan Jun 17, 2020

Immunology: What are toll-like receptors and how do they invoke tumor tolerance?

Toll-like receptors (TLR) are transmembrane receptors that play a critical role in innate immune res...
Tamar Aprahamian, PhD Jun 10, 2020

Epitope Tagging: The Importance of Antibody Selection

Biological research is about expanding knowledge, so it's not uncommon for scientists to study prote...
Tamar Aprahamian, PhD May 20, 2020

10 Must-have Markers for Senescence Research

Understanding when and why cell cycle arrest occurs is critical to many fields of research, includin...
Tamar Aprahamian, PhD May 13, 2020

Cell Process - How is cell proliferation quantified?

The production of new cells through cellular proliferation impacts the development, growth, and main...
Tamar Aprahamian, PhD Apr 22, 2020

Cell Process: What is cell viability and how can it be measured?

The health of cells in culture is critical to the success of your experiments. Have you ever been ex...
Tamar Aprahamian, PhD Apr 15, 2020

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