CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology® (CST) where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Hallmarks of Cancer: Genome Instability and Mutation

Not all cancer cells are equal, they evolve in response to selective pressure driven by accumulation...
Chris S Aug 28, 2019 3:10:00 AM

Hallmarks of Cancer: Tumor Promoting Inflammation

Cancer cells hijack inflammatory mechanisms to promote their own growth and survival. During a norma...
Chris S Aug 21, 2019 3:15:00 AM

Webinar | Linking Senescence with DNA Damage and the Cell Cycle

Gain insight into the processes by which senescent cells contribute to tumor suppression and age-rel...
Chris S Aug 14, 2019 3:10:00 AM

Hallmarks of Cancer: Activation Invasion and Metastasis

Cancer cells invade local tissue and spread to distant sites via two distinct, but similar processes...
Chris S Jul 17, 2019 3:15:00 AM

Hallmarks of Cancer: Avoiding Immune Destruction

Some cancer cells adapt mechanisms to evade detection and destruction by the host's immune system. O...
Chris S Jun 12, 2019 3:15:00 AM

Who am I: Can a cellular identity crisis lead to cancer progression?

            The process of epithelial-mesenchymal transition (EMT), whereby differentiated epithelia...
Antony W May 29, 2019 3:10:00 AM

What is Senescence?

Cellular senescence is defined by permanent cell cycle arrest. Senescent cells accumulate with age a...
Susan K May 22, 2019 3:15:00 AM

Hallmarks of Cancer: Evading Growth Suppressors

Cancer cells resist inhibitory signals that might otherwise stop their growth. The major pathways in...
Chris S May 1, 2019 3:10:00 AM

Hallmarks of Cancer: Enabling Replicative Immortality

Cancer cells can revert to a pre-differentiated, stem-cell-like phenotype, allowing uninhibited cell...
Chris S Apr 17, 2019 3:10:00 AM

Hallmarks of Cancer: Sustaining Proliferative Signaling

Cancer cells stimulate their own growth, which means they become self-sufficient in growth signals, ...
Chris S Apr 3, 2019 3:15:00 AM

Hypoxia and Cancer – the role of HIF-1α in oxygen sensing, metabolism, and tumorigenesis

Molecular oxygen (O2) is an essential element for metazoan life. Among its many roles, O2 functions ...
Jianxin X. Mar 27, 2019 3:10:00 AM

Hallmarks of Cancer: Inducing Angiogenesis Energetics

Cancer cells stimulate the growth of blood vessels to supply nutrients to tumors. Angiogenesis is th...
Chris S Mar 20, 2019 3:15:00 AM

Necroptosis and Pyroptosis Add to Our Understanding of Apoptotic Cell Death

Over the last 50 years laboratories have been able to demonstrate through experimentation the proces...
Gary K. Mar 13, 2019 3:05:00 AM

Hallmarks of Cancer: Deregulating Cellular Energetics

Cancer cells need a lot of energy to grow fast—to do so, they show abnormal metabolic pathways.
Chris S Feb 27, 2019 3:15:00 AM

Missing Link: Why Do Insulin-producing Cells in Type 2 Diabetes Fail to Divide?

Type 2 diabetes is a growing epidemic, and is recognized as one of the most serious metabolic diseas...
Neha G Jan 17, 2018 3:00:00 AM

Webinar | Advances in AMPK and Autophagy Signaling

Reuben Shaw, Ph.D Professor, Molecular and Cell Biology Laboratory, Deputy Director, Salk Cancer Cen...
Liana G Dec 20, 2017 6:15:00 AM

Intracellular Flow Cytometry in Action

Traditionally, flow cytometry has been used to identify distinct cell types within a heterogeneous p...
Liana G Aug 9, 2017 9:45:00 AM

3 Questions to ask before starting your next immunofluorescence experiment.

Specificity, consistency, and optimized assay conditions are three key elements that help ensure rel...
Liana G Oct 19, 2016 3:00:00 AM

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