Western blotting is used to detect proteins and analyze their expression using antibodies, but it does have its limitations. Flow cytometry also employs antibodies, but it uses fluorescence to detect and analyze protein expression on a cell-by-cell basis.
Understanding the microenvironment of disease is critical for the success of targeted therapies. For years, the complex landscape of the tumor microenvironment could only be studied in single-cell snapshots by flow cytometry or limited tissue staining. Advanced multiplexing technologies such as Imaging Mass Cytometry™ (IMC™) now enable the imaging of up to 40 protein markers on both the cellular and tissue level.
Have you ever wondered about the minds behind our antibodies? We talk a lot about validation, specificity, sensitivity, and reproducibility. All of that is very important, but that doesn't tell you much about who developed it.
If you haven’t heard already, it’s CST’s 20th anniversary. Woohoo! You could say this year is kind of a big deal for us. We have a lot to celebrate. However, once we started listing the successes over the years, we realized that we are most proud of what you – the researchers worldwide – have accomplished using our reagents. After all, we don’t live in a vacuum. We exist to serve you and enable important discoveries and the development of cures.
Today marks 20 years of impact in scientific research and community support. We haven't done this alone — you’ve inspired us to think bigger and tackle greater challenges— we’ve Created Something Together. Thank you for standing with us.
Topics: Corporate Social Responsibility
Not all cancer cells are equal, they evolve in response to selective pressure driven by accumulation of mutations. Cancer cells have to out-compete nearby cells for nutrients and other resources, avoid immune cell attack, and suppress apoptotic self-destruction.
Cancer cells hijack inflammatory mechanisms to promote their own growth and survival. During a normal inflammatory response by the innate and adaptive immune system, immune cells carry out their designated task of engulfing and/or destroying foreign invaders.
Gain insight into the processes by which senescent cells contribute to tumor suppression and age-related pathologies. This webinar explores the impact of senescence on age-related dysfunction and chronic disease and introduces potential therapies targeting senescent cells.
Cancer cells invade local tissue and spread to distant sites via two distinct, but similar processes known as invasion and metastasis.
Our immune system has the ability to detect and fight infectious pathogens. It can also detect when normal cells become cancerous and kill those cells, preventing cancer progression. But over time, cancers can evolve and evade the immune response.