CST BLOG

The official blog of Cell Signaling Technology, where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Understanding Mitophagy: Pathways, Disease Links, and Tools for Detection

Mitochondrial health is a complex, carefully regulated process involving pathways that determine mit...
Gary Kasof, PhDAug 11, 2021

Neuroinflammation in Neurodegenerative Diseases

Neuroinflammation is the activation of an immune response in the central nervous system (CNS; brain ...
Chris SumnerJun 23, 2021

Autophagy: Taking Out the Cellular Trash Has Widespread Therapeutic Implications

The term “autophagy” introduced by the biochemist Christian de Duve in 1963 is derived from the Gree...
Gary Kasof, PhDJun 16, 2021

Neurotransmitters, Receptors, and Transporters

Neurons are central nervous system (CNS) cells that receive and transmit electrochemical signals by ...
Chris SumnerMay 19, 2021

Which Antibody-Based Techniques Can Be Used to Study Neurodegenerative Diseases?

In order to derive the most information from samples related to neurodegenerative disease, it is imp...
Chris SumnerMar 17, 2021

Neurodegeneration: Tau Protein and Neurofibrillary Tangles

Tau is a microtubule-associated protein expressed predominantly in the parts of the brain that funct...
Chris SumnerFeb 10, 2021

What is Neurodegeneration?

Neurodegeneration is marked by the progressive loss of neuronal function and structure, leading to c...
Chris SumnerJan 20, 2021

Chasing Tau-biomarkers for Alzheimer’s Disease: Part 2

This is Part 2 of a two-part blog series on Alzheimer's Disease. Read Part 1 here. Finding a Diagnos...
Antonio V and Lei LJan 13, 2021

Chasing Tau-biomarkers for Alzheimer’s Disease: Part 1

Dementia is an inevitable burden for many, prevailing under a broad umbrella not only in neurologica...
Antonio V and Lei LDec 2, 2020

Tissue Clearing from a Microscope Enthusiast’s Perspective

Biological imaging data has massive potential in terms of complexity of experiment and richness of d...
Ginny Bain, PhDOct 30, 2019

Taking Out the Mitochondria in Parkinson’s Disease

We’re proud to partner with The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to move Pa...
Richard Cho, PhDJul 31, 2019

Tissue Clearing Imaging Methods for Whole, Intact Brain Imaging

For generations of neuroscientists, using immunohistochemistry to study the brain in its anatomical ...
Richard Cho, PhDJun 5, 2019

APOE4 & Insulin Receptor Signaling: A Hidden Link Between Diabetes & Alzheimer’s Disease?

You might be surprised to learn that diabetes, a metabolic disease, may be linked to the neurodegene...
Richard Cho, PhDAug 1, 2018

SfN 2017 Recap: Lonely Neuron No More

In November 2017, over 30,000 neuroscientists gathered in Washington D.C. to talk all things brain a...
Richard Cho, PhDDec 13, 2017

TREM2 Opens a Rabbit Hole of Questions for Alzheimer’s Researchers

It's almost time for the 2017 Society for Neuroscience meeting. To get your neurons excited for the ...
Richard Cho, PhDNov 8, 2017

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