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Immunology: What are myeloid cells and how are they identified?

During hematopoiesis, myeloid cells develop from a common myeloid progenitor (CMP) found in the bone...
Rob MacDonald, PhD May 22, 2025

Immunology: What are lymphoid cells and how are they identified?

In humans, hematopoietic stem cells (HSCs) continuously replenish all types of blood cells via a ser...
Amrik Singh, PhD May 21, 2025

Do mRNA and protein levels correlate? Not necessarily.

To what extent does mRNA dictate cellular protein levels? It depends. For decades, scientists have u...
Tyler Levy Apr 23, 2025

The Importance of the ISG15 Protein in COVID-19 Research

Historically, the ISG15 protein hasn’t been thoroughly investigated by researchers. We know it can f...

Xenophagy: What You Eat Can’t Hurt You

Xenophagy provides an important defense against foreign pathogens such as bacteria and viruses by ta...
Gary Kasof, PhD Sep 15, 2021

Immunology: Immunophenotyping Using Flow Cytometry or IHC

In the field of immunology and immuno-oncology, immunophenotyping is a technique that uses antibodie...
Chris Sumner Jun 30, 2021

Neuroinflammation in Neurodegenerative Diseases

Neuroinflammation is the activation of an immune response in the central nervous system (CNS; brain ...
Chris Sumner Jun 23, 2021

Mechanisms of Cell Death: Pyroptosis

Under the category of necrotic cell death, there are many well-characterized, as well as some newly ...
April Lowell, PhD Apr 7, 2021

Case Study: Acetylated Lysine and Its Impact on Crohn’s Disease

Nature Communications recently published a novel study from the laboratory of Daniel Figeys at the U...

B Cell Basics: Markers, Signaling Pathways & Immune Outcomes

Changes in the activation of intracellular signaling networks downstream of B-cell receptors (BCR) l...
Tamar Aprahamian, PhD Nov 18, 2020

T Cell Basics: What a Disease Researcher Needs to Know

T cells are highly specialized lymphocytes that play a critical role in the cell-mediated arm of the...
Tamar Aprahamian, PhD Nov 11, 2020

COVID-19 and Fibrosis: Long-term Damage Beyond Acute Respiratory Symptoms

At the time of writing, the SARS-CoV-2 virus, responsible for COVID-19, has infected more than 28 mi...
Antony Wood, PhD Nov 4, 2020

The Role of Autophagy and ER Stress in Viral Infection

The regulation of ER stress and autophagy during viral infection is an important factor in the balan...
Gary Kasof, PhD Oct 28, 2020

The Role of Cell Death in Viral Infection

The regulation of cell death during viral infection is an important factor in the balance of virus a...
Gary Kasof, PhD Oct 21, 2020

How can recombinant proteins help researchers study SARS-CoV-2?

Although coronaviruses have long circulated throughout human populations, the study of these viruses...
Tamar Aprahamian, PhD Aug 5, 2020

Immunology: How does the adaptive immune system work?

Have you ever wondered how people are able to develop immunity to specific diseases? This important ...
April Lowell, PhD Jul 29, 2020

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