CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Interrogating Immunometabolism in the TME Using a Metabolic Checkpoint

Previously considered distinct disciplines, the fields of immunology and metabolism are converging i...
Jianxin Xie, PhD Apr 17, 2024

Faster CAR-T Cell Detection with Flow Cytometry-Validated Anti-CAR Linker Antibodies

CST® anti-CAR linker antibodies won The Innovation Award from CiteAb in 2023. Read on to learn why! ...
Amrik Singh, PhD Nov 8, 2022

The Importance of the ISG15 Protein in COVID-19 Research

Historically, the ISG15 protein hasn’t been thoroughly investigated by researchers. We know it can f...

Immunology: Which Cells Have a Lymphoid Lineage and How Are They Identified?

In humans, hematopoietic stem cells (HSCs) continuously replenish all types of blood cells via a ser...
Emma E Jan 19, 2022

Using SignalScan to Investigate Infection and Immune Response

The highly contagious severe acute respiratory syndrome coronavirus-2 or SARS-CoV-2 is the cause of ...

Immunology: Immunophenotyping Basics

Immunophenotyping is a technique that uses antibodies to allow the identification and quantification...
Chris Sumner Jun 30, 2021

Case Study: Acetylated Lysine and Its Impact on Crohn’s Disease

Nature Communications recently published a novel study from the laboratory of Daniel Figeys at the U...

B Cell Basics: What a Disease Researcher Needs to Know

Changes in the activation of intracellular signaling networks downstream of B-cell receptors (BCR) l...
Tamar Aprahamian, PhD Nov 18, 2020

T Cell Basics: What a Disease Researcher Needs to Know

T cells are highly specialized lymphocytes that play a critical role in the cell-mediated arm of the...
Tamar Aprahamian, PhD Nov 11, 2020

COVID-19 and Fibrosis: Long-term Damage Beyond Acute Respiratory Symptoms

At the time of writing, the SARS-CoV-2 virus, responsible for COVID-19, has infected more than 28 mi...
Antony Wood, PhD Nov 4, 2020

The Role of Cell Death in Viral Infection

The regulation of cell death during viral infection is an important factor in the balance of virus a...
Gary Kasof, PhD Oct 21, 2020

How can recombinant proteins help researchers study SARS-CoV-2?

Although coronaviruses have long circulated throughout human populations, the study of these viruses...
Tamar Aprahamian, PhD Aug 5, 2020

Immunology: How does the adaptive immune system work?

Have you ever wondered how people are able to develop immunity to specific diseases? This important ...
April Lowell, PhD Jul 29, 2020

Immunology: What are toll-like receptors and how do they invoke tumor tolerance?

Toll-like receptors (TLR) are transmembrane receptors that play a critical role in innate immune res...
Tamar Aprahamian, PhD Jun 10, 2020

Immunology: Which cells have a myeloid lineage and how are they identified?

During hematopoiesis in humans, cells of the myeloid lineage are derived from a common myeloid proge...
Tamar Aprahamian, PhD May 27, 2020

Fibrosis: When Wound Healing Turns to Disease

Fibrosis is a disease that is characterized by scarring and hardening of tissues and organs. Fibrosi...
Susan Keezer, PhD Mar 25, 2020

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