CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

How to Detect Protein Methylation

Protein methylation is a ubiquitous and critical post-translational modification (PTM) in eukaryotes...

Got the 'NOS'? Fueling Research with New Nitro-Tyrosine Antibody Tools

Since 2000, Cell Signaling Technology (CST) has offered a rigorously tested and well-cited polyclona...

Reproducibility in Proteomics Experiments: Using Control Peptides with PTMScan

Proteomics, the large-scale analysis of proteins, has become an increasingly important tool for iden...

The Kinase Library: How a Collaboration Between Cornell, MIT, Yale & CST is Elucidating Cellular Pathways

Protein kinases play a vital role in the regulation of nearly all cellular activities. Through phosp...
Alexandra Foley May 3, 2023

A Revolution in Proteomics Analysis: PTMScan 20 Years Later

Twenty years ago, when considering the tools needed for more robust proteomics research to probe cel...

It's All about the Affinity

In 2012 Roux et al. published in the Journal of Cell Biology a pioneering approach to identify the i...

Antibodies for Identifying the Protein Modification O-GlcNAc

Rajan Burt, Samuel Myers, and colleagues from the La Jolla Institute for Immunology, Broad Institute...

Case Study: Acetylated Lysine and Its Impact on Crohn’s Disease

Nature Communications recently published a novel study from the laboratory of Daniel Figeys at the U...
Charles F and Josh N Dec 16, 2020

Taking Out the Mitochondria in Parkinson’s Disease

We’re proud to partner with The Michael J. Fox Foundation for Parkinson’s Research (MJFF) to move Pa...
Richard C and Yiying Z Jul 31, 2019

Webinar | Proteomics profiling of post-translational modifications in early drug discovery

Advances in mass spectrometry instrumentation and sample handling methods have propelled proteomics ...
Chris Sumner Mar 28, 2018

The Potential of Proteomics: A Clear Path to Discovery | Part II

See a real life example of how PTMScan technology can facilitate translational discovery. In this sh...
Carolyn P Feb 22, 2017

The Potential of Proteomics: A Clear Path to Discovery

Whether your lab is well-versed and equipped to do Mass Spec analysis in-house or your lab has never...
Carolyn P Jan 11, 2017

Simplifying Proteomics - Part I

After sequencing of the human genome was complete, it was time to roll up our sleeves and get starte...
Claire S Jun 15, 2016

Webinar - Simplify Proteomics

Post Translational Modification: Antibody Enrichment for Mass Spectrometry-based Proteomics Continui...
Claire S Dec 16, 2015

Simplifying Proteomics - Part 3

Part 1 and part 2 introduced mass spectrometry-based proteomic methods, like PTMScan®, for the study...
Claire S Dec 9, 2015

Simplifying Proteomics - Part 2

Part 1 gave an overview on mass spectrometry-based proteomics. Now, it’s time to talk about how this...
Claire S Dec 2, 2015

PTMScan Tutorial Video

Simplifying proteomics Part 1 introduced mass spectrometry-based proteomics for profiling post-trans...
Claire S Jun 10, 2015

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