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The official blog of Cell Signaling Technology, where we discuss what to expect from your time at the bench, share tips, tricks, and information.

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Will PTMScan® Antibodies Work in My Species or Model Organism?

We frequently get this question from scientists: “Which species do your PTMScan antibodies work in?”
Barry Zee May 6, 2026

How DIA Proteomics Can De‑Risk Targeted Protein Degradation (TPD) Programs

Targeted Protein Degradation (TPD) programs are moving fast, but many still stall out at the same ro...
Jeffrey Silva, PhD Apr 2, 2026

Automating PTM Profiling for Mass Spec: Scalable Proteomics Workflows Using PTMScan® Reagents

Studying post-translational modifications (PTMs) is critical for advancing our understanding of cell...
Barry Zee Jul 16, 2025

How to Detect Protein Methylation Using Proteomics

Protein methylation is a ubiquitous and critical post-translational modification (PTM) in eukaryotes...

Got the 'NOS'? Fueling Research with New Nitro-Tyrosine Antibody Tools

Since 2000, Cell Signaling Technology (CST) has offered a rigorously tested and well-cited polyclona...

How to Use Control Peptides with PTMScan Proteomics

Proteomics, the large-scale analysis of proteins, has become an increasingly important tool for iden...

A Revolution in Proteomics Analysis: PTMScan 20 Years Later

Twenty years ago, when considering the tools needed for more robust proteomics research to probe cel...

Antibodies for Identifying the Protein Modification O-GlcNAc

Rajan Burt, Samuel Myers, and colleagues from the La Jolla Institute for Immunology, Broad Institute...

The Importance of the ISG15 Protein in COVID-19 Research

Historically, the ISG15 protein hasn’t been thoroughly investigated by researchers. We know it can f...

Understanding the Proteome: An Introduction to Mass Spectrometry-Based Proteomics

After sequencing of the human genome was complete, it was time to roll up our sleeves and get starte...
Claire S Jun 15, 2016

From Discovery to Diagnostics: Translational Applications of PTM Proteomics

Part 1 and part 2 introduced mass spectrometry-based proteomic methods, like PTMScan® technology, fo...
Claire S Dec 9, 2015

Enriching for PTMs: Antibody-Based Strategies for Proteomics Analysis

In part one, Understanding the Proteome: An Introduction to Mass Spectrometry-Based Proteomics, we g...
Claire S Dec 2, 2015

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