CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology® (CST) where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Tools for Determining Protein State

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Tools for Determining Protein State

Post-translational modifications (PTMs) are a critical regulatory mechanism that allows cells to tig...
Andrea T Dec 8, 2021 3:00:00 AM

Case Study: Acetylated Lysine and Its Impact on Crohn’s Disease

Nature Communications recently published a novel study from the laboratory of Daniel Figeys at the U...
Charles F and Josh N Dec 16, 2020 3:00:00 AM

Studying Post-translationally Modified Sites and Disease Variants with PhosphoSitePlus®

Post-translational modifications (PTMs) are employed in the cell to alter protein function, and typi...
Florian G. Feb 13, 2019 3:10:00 AM

Myth-busting for ChIP/ChIP-seq: Mono vs. Poly

Researchers who run a lot of chromatin immunoprecipitation "ChIP" assays – maybe even your advisor –...
Neha G and Ken B Sep 26, 2018 3:15:00 AM

Have You Ever Wondered: What's The Lowdown on Phospho-Specific Antibodies?

Early exploration of unmapped biological signaling pathways were carried out using radiolabeled phos...
Ken B Jul 26, 2017 3:20:00 AM

Successful Immunofluorescence: Experimental Controls

 Part two of a four-part series on Immunofluorescence. Check out our posts on Validation and Fixatio...
Ken B Mar 8, 2017 3:00:00 AM

Simplifying Proteomics - Part 2

Part 1 gave an overview on mass spectrometry-based proteomics. Now it’s time to talk about how this ...
Claire S Feb 8, 2017 10:40:01 AM

Simplifying Proteomics - Part I

After sequencing of the human genome was complete, it was time to roll up our sleeves and get starte...
Claire S Jun 15, 2016 3:00:00 AM

Simplifying Proteomics - Part 3

Part 1 and part 2 introduced mass spectrometry-based proteomic methods, like PTMScan®, for the study...
Claire S Dec 9, 2015 3:00:00 AM

Simplifying Proteomics - Part 2

Part 1 gave an overview on mass spectrometry-based proteomics. Now it’s time to talk about how this ...
Claire S Dec 2, 2015 3:00:00 AM

Simplifying Proteomics - Part I

After sequencing of the human genome was complete, it was time to roll up our sleeves and get starte...
Claire S Nov 23, 2015 3:00:00 AM

PTMScan Tutorial Video

Simplifying proteomics part 1 introduced mass spectrometry-based proteomics for profiling post-trans...
Claire S Jun 10, 2015 5:30:00 AM

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