CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

What is a Recombinant Antibody and Why is it Important?

Recombinant antibodies offer several key advantages compared to traditional antibodies. These includ...

The Importance of Research Antibody Specificity and Reproducibility During the SARS-CoV-2 Crisis

During this time of crisis, healthcare providers and researchers around the world are racing to deve...

Hallmarks of Validation - Complementary Strategies

Depending on the antigenic target being studied and the application being used, it may be advisable ...
Katie Crosby Apr 8, 2020

Hallmarks of Antibody Validation: Heterologous Strategy

For antigenic targets where expression of the protein is very low or unknown, the use of recombinant...
Katie Crosby Apr 1, 2020

Hallmarks of Validation - Multiple Antibody Strategy

A multiple antibody strategy is a powerful approach to antibody validation. One of the most common m...
Katie Crosby Mar 18, 2020

CiteAb Awards: Antibody Supplier of the Decade & Antibody Supplier Succeeding in Alzheimer's Research

We’re honored to win two CiteAb awards in 2020: Antibody Supplier of the Decade and Antibody Supplie...
Chris Sumner Mar 11, 2020

Hallmarks of Validation - Ranged Strategy

While a binary approach is one of the more desirable ways to evaluate antibody specificity, binary m...
Katie Crosby Feb 19, 2020

Hallmarks of Antibody Validation - Binary Strategy

A binary approach is one of the best ways to evaluate antibody specificity. By testing an antibody i...
Katie Crosby Jan 22, 2020

Video: Can you trust your immunohistochemistry results?

Immunohistochemistry, or IHC, remains the simplest method for detecting biomarker expression while m...
Chris Sumner Jun 19, 2019

What makes an antibody monoclonal, polyclonal, or recombinant?

When you’re shopping for antibodies, there are so many factors to consider. For example, will it wor...
Chris Sumner Jan 30, 2019

Science: Disrupt | Responsible Science Podcast Series

We're excited to partner with Science: Disrupt to present a five-part podcast exploring what "Respon...

Antibody Validation 101

As a development scientist at CST, people sometimes ask me what exactly it is that I do. “I make ant...
Susan Keezer, PhD Mar 7, 2018

CST is the CiteAb 2018 Antibody Company of the Year!

We, as scientists, learn from each success and failure. Sometimes it takes many failures to achieve ...
Chris Sumner Feb 7, 2018

Successful Immunofluorescence: The Importance of Validation

Part 1 of a four-part series on successful immunofluorescence. Read Part 2: Experimental Controls, P...
Kenneth Buck, PhD Mar 1, 2017

The Reproducibility Crisis: An Open Letter from Our Chief Scientific Officer

A Message from our Chief Scientific Officer, Roberto Polakiewicz, Ph.D. The time is now for the scie...
Carolyn P Aug 10, 2016

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