CST BLOG: Lab Expectations

The official blog of Cell Signaling Technology (CST), where we discuss what to expect from your time at the bench, share tips, tricks, and information.

Lab Expectations listing page

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Key Epithelial-Mesenchymal Transition (EMT) Markers in Cancer

EMT, or epithelial-mesenchymal transition, is a biological process in which epithelial cells gain th...
Susan Keezer, PhD Jun 4, 2025

Targeting the Tumor Microenvironment: Key Markers of the ECM

In recent years, cancer researchers have started paying closer attention to the extracellular matrix...
Susan Keezer, PhD May 28, 2025

Watch Your Bax: How a Faulty Antibody May Have Cost Millions in Flawed Research

Science is a collaborative effort—a joint pursuit where each discovery builds on the foundation buil...
Alexandra Foley Apr 9, 2025

Microglial Activation Antibody Toolkit: High-Content Methods to Study TREM2 Signaling

Selecting antibodies for molecular signaling research in neurodegeneration is a complex and nuanced ...
Ginny Bain, PhD Jan 8, 2025

500 Antibodies & Counting: How Are CST Antibodies Validated for Simple Western Technology?

Since 2022, Cell Signaling Technology (CST) and Bio-Techne have been working together to bring best-...
Chris LaBreck, PhD Oct 23, 2024

How to Detect the ADP-Ribosylation PTM Using a Monoclonal Antibody

Protein adenosine diphosphate, or ADP-ribosylation, is a fascinating post-translational modification...

Unraveling Alzheimer’s Disease: Developing a P-Tau 217 Antibody

With Alzheimer’s disease (AD) set to affect more than 7.1 million people over 65 worldwide by 2025, ...
Arica Aiello Aug 14, 2024

Antibody Validation for IHC: Finding a Claudin-6 mAb Clone

Developing research antibodies is an extensive process that takes advantage of an animal’s adaptive ...
Alexandra Foley Nov 15, 2023

IHC-Validated p16 INK4A Antibody: Jump-Start Your Senescence Research

Cell cycle regulation is vital to maintain tissue homeostasis and to prevent sustained proliferative...
Andrea Tu, PhD Apr 19, 2023

CST® Antibodies Validated on the Leica Microsystems Cell DIVE Multiplexed Imaging Solution

True innovation comes from collaboration–from bringing experts together to create techniques and too...
Alexandra Foley Mar 15, 2023

Targeting TIGIT for Cancer Immunotherapy & T Cell Exhaustion

The evolution of solid tumor cancer treatment has historically centered on a tripartite approach tha...
Tamar Aprahamian, PhD Feb 17, 2021

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