Webinar | Linking Senescence with DNA Damage and the Cell Cycle


Posted by Chris S on Aug 14, 2019 3:10:00 AM

Gain insight into the processes by which senescent cells contribute to tumor suppression and age-related pathologies. This webinar explores the impact of senescence on age-related dysfunction and chronic disease and introduces potential therapies targeting senescent cells.

 
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Topics: Cell Biology, Webinars

Webinar | Deciphering Neurodegeneration: Inflammation, immune response, and Alzheimer's


Posted by Chris S on Nov 14, 2018 3:15:00 AM

Hear about the potential role of innate immunity in neurodegeneration and cognitive function, particularly in Alzheimer's disease. Learn how immune-related pathways regulate the development, refinement, and elimination of specific axons and synapses during development. Gain an understanding of how recent work can provide insight into protecting synapses in neurodegenerative and psychiatric disorders of synaptic dysfunction.

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Topics: Webinars

2018 Nobel Prize Awarded to Immunotherapy Pioneers


Posted by Cell Signaling Technology on Oct 3, 2018 3:00:00 AM

Earlier this week, Dr. James Allison and Dr. Tasuku Honjo were announced as joint winners of the 2018 Nobel Prize in Physiology or Medicine for their work in the field of immunotherapy and checkpoint immune regulation. Their studies have sparked decades of clinical advances, and changed the future of cancer therapy. A webinar presented by Dr. Allison in conjunction with Dr. Gordon Freeman and Dr. Philip Gotwals is featured in this week's blog post.

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Topics: Cancer Immunology, Cancer Research, Webinars, Immunotherapy

Targeting Cancer Pathways - Tumor Metabolism and Proliferation


Posted by Carolyn P on Jul 25, 2018 3:10:00 AM


Cell Signaling Technology is proud to partner with the Koch Institute at MIT, Science, and Science Signaling to present the Targeting Cancer Pathways webinar series. These webinars will bring together thought leaders from around the world to share current findings and further cancer research community collaboration.

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Topics: Cancer Research, Webinars

Webinar | Proteomics profiling of post-translational modifications in early drug discovery


Posted by Chris S on Mar 28, 2018 3:15:00 AM

Advances in mass spectrometry instrumentation and sample handling methods have propelled proteomics and extended its utility for both basic biology and early drug development. Changes in protein abundance and post-translational modification state often reflect the activity of a novel therapeutic agent as well as the sensitivity/resistance of a biological system to treatment.

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Topics: Proteomics, Webinars

Webinar | Achieving Reproducibility: Don't Let Antibodies Be a Variable in Your Experiment


Posted by Chris S on Jan 10, 2018 6:30:00 AM

The importance of antibodies as tools in scientific research studies cannot be understated, yet these reagents have increasingly come under fire for their lack of reproducibility. Part of the issue is that the antibody market is composed of hundreds of vendors and resellers with varying definitions for validation and consistency. Cell Signaling Technology (CST) believes that antibody suppliers should be held accountable for the products they provide, but that vendors alone cannot solve the reproducibility “crisis." How antibodies are validated and used in the laboratory is a critical component to this process. Researchers need to be more attentive to following established protocols and leverage the expertise of the scientists who have developed and tested the product they are using. Journals need to be more active in enforcing existing policies regarding materials and methods or develop more clear-cut means to identify and describe the use of biological reagents in published research. During this webinar we will address the role vendors, researchers, and journals should play in minimizing irreproducibility. We will also outline CST’s antibody validation process, while highlighting steps all users should consider when selecting and using antibodies in their research.

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Topics: Antibody Performance, Antibody Validation, Webinars, Reproducibility

Targeting Cancer Pathways - Tumor Resistance


Posted by Carolyn P on Oct 18, 2017 6:00:00 AM


Cell Signaling Technology is proud to partner with the Koch Institute at MITScience, and Science Signaling to present the Targeting Cancer Pathways webinar series. These webinars bring together thought leaders from around the world to share current findings and further cancer research community collaboration.

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Topics: Cancer Research, Webinars

Discovery Through Validation: ChIP Assays


Posted by Carolyn P on Aug 2, 2017 8:45:00 AM

Cell Signaling Technology is proud to present the following On-Demand Webinar: 

The Use of Highly Validated Antibodies and Optimized ChIP Assays to Analyze Epigenetic Marks and Mechanism in DIsease

Sayura Aoyagi, Ph.D, CST Antibody Validation Scientist

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Topics: Cancer Research, Webinars, Reproducibility

Webinar | Deciphering cancer: The intersection of epigenetics, metabolism, and tumorigenesis


Posted by Chris S on Apr 5, 2017 3:00:00 AM

Epigenetic modifications to DNA and histone proteins are known to regulate metabolic gene expression, which in turn impacts metabolite levels. Conversely, the machinery responsible for modifying DNA and histones at the epigenetic level is highly sensitive to metabolites arising from cellular metabolism. . .

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Topics: Webinars

Webinar | Key signaling pathways in cancer: Emerging trends in immunometabolism


Posted by Carolyn P on Mar 22, 2017 7:00:00 AM

 

Immune cells divide rapidly when mounting an immune response against a pathogen, for example, or when initiating a wound-healing response. To accommodate the increased energy requirements to mount the immune response, these cells may employ metabolic pathways similar to those engaged by cancer cells—pathways such as aerobic glycolysis. This correlation presents the intriguing possibility that understanding immune cell metabolism will provide new and actionable insights into the behavior of tumor cells. In this webinar, our expert speakers will explore how this phenomenon is being studied and describe how it could enable the development of new strategies in the fight against cancer. 

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Topics: Cancer Immunology, Cancer Research, Webinars

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