The Reproducibility Crisis: An open letter from CST's Chief Scientific Officer

Posted by Carolyn P on Aug 10, 2016 3:00:00 AM

A Message from our Chief Scientific Officer, Roberto Polakiewicz, Ph.D.

The time is now for the scientific community to come together to respond to the challenges of reproducibility and to be part of the solution . . . 


Topics: Reproducibility

CRISPR: Science magazine’s 2015 breakthrough of the year

Posted by Liana G on Jun 29, 2016 3:30:00 AM

CRISPR, a nifty gene-editing tool, has swept the scientific community off its feet. It has a catchy name, it’s in every other publication, it is the subject of a volatile legal dispute involving claims to its intellectual property (1), its use has instigated a multitude of summits to do with its ethical ramifications and, despite the fact that it’s less than 4 years old, the Science journal named it the ‘breakthrough of the year’ (2). To give you some perspective, the other contenders were the New Horizon’s epic visit to the dwarf planet Pluto, the discovery of a lymphatic system in the brain, and the Ebola vaccine. 

Well, you get the picture, CRISPR is a big deal, but what on Earth is it and why are scientists so smitten by it?


Topics: Literature Review, Reproducibility

Roundtable Discussion on Antibody Validation

Posted by Carolyn P on Feb 17, 2016 3:00:00 AM

Antibody Validation Roundtable: Specificity + Sensitivity + Reproducibility = Validation 

Concerns about the use of incorrectly or insufficiently characterized antibodies in biomedical research have been raised by recent reports of nonreproducible research studies. Non-reproducible research studies have resulted in loss of time, resources, and scientific reputation, with publication retractions occurring in certain cases.


Topics: Antibody Performance, Primary Antibodies, Antibody Validation, Webinars, Reproducibility

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