BioPlex: a protein interaction network created from thousands of protein immunopurifications
Steven Gygi, Ph.D
Professor in the Department of Cell Biology, Harvard Medical School
Protein-protein interactions form a network whose structure drives cellular function and whose organization informs all biological inquiry. Using high-throughput affinity-purification mass spectrometry, we identify interacting partners for 2,594 human proteins in HEK293T cells. The resulting network (BioPlex) contains...