Webinar | Deciphering Cancer: Genomic Instability in Cancer

Posted by Carolyn P on Nov 30, 2016 3:00:00 AM


While it is well established that DNA damage can increase the risk of cancer, changes to the epigenome or the chromatin architecture are equally important. DNA damage triggers a redistribution of DNA-binding proteins around the site of damage, resulting in localized and temporary alteration of chromatin structure. However, repeated cycles of DNA damage and repair may lead to permanent changes in the epigenome, thereby promoting the onset of diseases such as cancer. This webinar will examine how we may be able to develop effective new therapeutic options for cancer treatment by targeting proteins responsible for chromatin modifications.


Topics: Cancer Immunology, Cancer Research, Webinars

Webinar | Targeting Cancer Pathways: Understanding Immune Checkpoints

Posted by Carolyn P on Aug 17, 2016 3:00:00 AM

In this webinar, the speakers will explore how tumors exploit immune modulatory mechanisms to generate and thrive in their own immunosuppressive microenvironment. In addition, they will:

Topics: Cancer Immunology, Cancer Research, Webinars

Webinar | Key Signaling Pathways in Cancer: Links to Developmental Biology

Posted by Carolyn P on Jul 27, 2016 3:00:00 AM

It is notable that the same pathways governing the cell growth, death, and differentiation decisions made during embryonic development are also common drivers of adult malignancy. In this webinar, we will explore the idea that a better understanding of developmental biology signaling pathways will advance our understanding of adult tumors and cancer stem cells as well as boost our ability to create effective therapeutics to fight a broad array of cancers.


Topics: Developmental Biology, Webinars

Webinar - BioPlex: a protein interaction network created from thousands of protein immunopurifications

Posted by Claire S on Apr 27, 2016 3:00:00 AM

BioPlex: a protein interaction network created from thousands of protein immunopurifications

Steven Gygi, Ph.D
Professor in the Department of Cell Biology, Harvard Medical School

Protein-protein interactions form a network whose structure drives cellular function and whose organization informs all biological inquiry. Using high-throughput affinity-purification mass spectrometry, we identify interacting partners for 2,594 human proteins in HEK293T cells. The resulting network (BioPlex) contains...


Topics: Webinars

Roundtable Discussion on Antibody Validation

Posted by Carolyn P on Feb 17, 2016 3:00:00 AM

Antibody Validation Roundtable: Specificity + Sensitivity + Reproducibility = Validation 

Concerns about the use of incorrectly or insufficiently characterized antibodies in biomedical research have been raised by recent reports of nonreproducible research studies. Non-reproducible research studies have resulted in loss of time, resources, and scientific reputation, with publication retractions occurring in certain cases.


Topics: Antibody Performance, Primary Antibodies, Antibody Validation, Webinars, Reproducibility

Targeting Cancer Pathways - Tumor Metabolism and Proliferation

Posted by Carolyn P on Jun 24, 2015 8:00:00 AM

Cell Signaling Technology is proud to partner with the Koch Institute at MIT, Science, and Science Signaling to present the Targeting Cancer Pathways webinar series. These webinars will bring together thought leaders from around the world to share current findings and further cancer research community collaboration.


Topics: Cancer Research, Webinars

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