WEBINAR | Key signaling pathways in cancer: Emerging trends in immunometabolism 

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Originally aired: Thursday, October 13, 2016


Duration: 1 hour

Immune cells divide rapidly when mounting an immune response against a pathogen, for example, or when initiating a wound-healing response. To accommodate the increased energy requirements to mount the immune response, these cells may employ metabolic pathways similar to those engaged by cancer cells—pathways such as aerobic glycolysis. This correlation presents the intriguing possibility that understanding immune cell metabolism will provide new and actionable insights into the behavior of tumor cells. In this webinar, our expert speakers will explore how this phenomenon is being studied and describe how it could enable the development of new strategies in the fight against cancer.

During the webinar, our expert speakers will:

  • Describe how aerobic glycolysis contributes to energy production in immune cells
  • Elucidate the role of lipid metabolism and mitochondrial remodeling in T-cell metabolism
  • Explain how metabolic changes impact the inflammation response and innate immunity.
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Presenter
Speaker: Luke O'Neill, Ph.D.
Trinity College Dublin
Dublin, Ireland
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Presenter
Speaker: Erika L. Pearce, Ph.D.
Max Planck Institute of Immunobiology and Epigenetics
Freiburg, Germany
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Presenter
Moderator: Sean Sanders, Ph.D.
Science/AAAS
Washington, DC
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