WEBINAR | Key signaling pathways in cancer: Links to developmental biology
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Originally aired: Thursday, June 2, 2016
Duration: 1 hour
It is notable that the same pathways governing the cell growth, death, and differentiation decisions made during embryonic development are also common drivers of adult malignancy. In this webinar, we will explore the idea that a better understanding of developmental biology signaling pathways will advance our understanding of adult tumors and cancer stem cells as well as boost our ability to create effective therapeutics to fight a broad array of cancers.
During the webinar, our speakers will:
- Discuss the mechanisms and control of antiproliferation signaling from cytokines such as transforming growth factor beta (TGF-β) and their role in cancer progression
- Explain the role of the Hedgehog signaling pathway in embryonic development and how it is deregulated in certain skin cancers and in pancreatic cancer
- Elucidate how the microenvironment impacts the behavior of tissue stem cells and how this crosstalk goes awry in cancer.
